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Scientists have discovered a pattern of molecules that appear in the blood before seizures, which could lead to the development of an early warning system for patients with epilepsy.
According to the researchers involved in this study, published in the Journal of Clinical Investigation, tRNAs are cut into fragments when cells are stressed. Higher levels of fragments in the blood might reflect the fact that brain cells are under stress during the onset of a seizure.
Using blood samples from people with epilepsy, the researchers found that fragmentary levels of three tRNAs "soared" in the blood several hours before a seizure.
"People with epilepsy often report that one of the most difficult aspects of living with the disease is to never know when a seizure will occur," said Dr. Marion Hogg, FutureNeuro's researcher. and lead author of the study.
"The results of this study are very promising, and we hope that our tRNA research will be an essential first step towards developing an early warning system."
The World Health Organization estimates that more than 50 million people in the world suffer from epilepsy.
"New technologies to remove the unpredictability of uncontrolled epileptic seizures in epileptics are a very real possibility," said Professor David Henshall, director of FutureNeuro and co-author of the paper.
(This story has not been changed by Business Standard staff and is generated automatically from a syndicated feed.)
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