Climate change may have an impact on the risk of congenital heart abnormality



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Exposure to maternal warmth due to climate change appears to be increasing, with more intense and longer-lasting heat episodes expected in the US by 2030. A new study has established a link between l / o. Maternal exposure to extreme heat during the first weeks of pregnancy and an increased risk for future conbad heart disease.

The researchers sought to identify the link between potential changes in heat exposure in pregnant women 3 to 8 weeks after conception and conbad heart defects.

"Previous studies have shown a positive relationship between extreme heat exposure and adverse reproductive outcomes, including prematurity and underweight at birth," Wangjian Zhang, MD, PhD, Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China, and colleagues wrote. "More importantly, two recent studies have shown an badociation between maternal exposure to heat in early pregnancy and an increased likelihood of conbad heart defects, the most common group of birth defects and one of the most common causes of morbidity and mortality in infants in the United States. "

Lin and colleagues evaluated data from the National Study on Conbad Anomaly Prevention, a large, multi-site, large population, case-control study that examined the risk factors for major structural conbad anomalies in the United States. -United.

The researchers defined several indicators of heat exposure and applied the published ORs of conbad heart defects from baseline conditions from 1995 to 2005 over a projection period of 2025 to 2035.

The researchers projected an increase in maternal heat exposure in all regions of the United States in the spring and summer, with a particularly high increase expected in the US Midwest for maternal exposure in the summer to very hot days (OR = 3.42, 95% CI, 2.99 to 3.88 per pregnancy) and duration of heat episodes (OR = 1.73, 95% CI: 1.49-1.97 ).

Lin and colleagues also identified an badociation between maternal heat exposure and some subtypes of conbad heart disease in the spring, with larger increases in subtypes of conbad conbad heart disease in the South (increasing 34%, 95% CI, 4.9 to 70.8) and Northeast Atrial Sepsis (38.6% increase, 95% CI, 9.9 to 75.1).

This study is the first to estimate the future changes in maternal exposure to heat and the badociated burden on conbad heart disease. The results provide useful metrics and maps for policymakers involved in preparing and allocating resources for adaptation to climate change, according to the researchers.

"Increases in exposure could be greater in the summer, especially in the Midwest, followed by the Northeast and South," Lin and his colleagues wrote. "However, the increases in [conbad heart defect] The disease burden may be higher in the spring, particularly in the southern and northeastern regions of the country for the septal and conotruncal cases. [conbad heart defects]. " – by Earl Holland Jr.

Disclosures: The authors do not report any relevant financial information.

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