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Scientists say that LOW-CALORIE diets can help prevent asthma symptoms.
It does not matter how much fat or sugar you eat, they say, as long as you consume less energy in general.
PA: Press Association
In a new study, they discovered that obesity resulting from a high-calorie diet can lead to asthma symptoms in animals following inflammation of the lungs.
Scientists say their findings prove a link between obesity, inflammation and asthma.
But they also found in their study that an anti-inflammatory relieved the symptoms of asthma in mice, which led them to conclude that it could be useful to treat obese people with respiratory difficulties with a similar medicine.
"Previous studies suggested that high fat or sugar diets that led to obesity promoted inflammation and caused asthma," said Dr. Vsevolod Polotsky, a professor of lungs and intensive care at the Johns Hopkins University School of Medicine, and lead author of the study.
Getty – Contributor
"However, our study shows that obesity causes asthma symptoms related to inflammation, regardless of the composition of the diet, and that a caloric restriction by any way can prevent or treat asthma by reducing inflammation. "
Dr. Polotsky said his team's study aimed to confirm the links between obesity, asthma, diet and inflammation, as well as to develop new potential treatment options.
Steroids inhalers do not work as well for obese asthmatics.
The study consisted of feeding normal male mice with one of four diets.
Getty – Contributor
The first was a low calorie diet (crisp pellet foods). The second was a high calorie diet with more fat per gram. The third was a high calorie diet with more fat and sugar per gram. The fourth type consisted of a high-calorie diet rich in processed sugars.
There were other groups of mice fed on high calorie diets, but their daily intake of food was limited to match the number of calories mice consumed with a low calorie diet.
After eight weeks, the mice under one of the low calorie diets gained at least 7 g more than mice on a low calorie diet or those on a high calorie diet.
The researchers then tested the lung function of rodents to see if the mice developed asthma symptoms.
Symptoms of asthma
Asthma is a respiratory condition caused by inflammation of the breathing tubes that carry air between our lungs and lungs. It currently affects more than 5 million people in the UK.
According to the NHS, the main symptoms of asthma are:
- Wheezing (hissing while breathing)
- breathlessness
- A tight chest
- Cough
They found that the radio waves of high calorie and unrestricted dietary mice were limited at least 6.3 times higher than the baseline.
The next step in the study was to inject a group of mice with a drug called anakinra each day in the last two weeks to block the activity of an inflammatory protein.
Anakinra tends to be used to treat rheumatoid arthritis because of its anti-inflammatory properties.
When obese mice were tested again after taking this medication, their airways narrowed only 2.9 times more than the baseline – 5.1 times less than obese mice that did not have it received.
Asthma is a common chronic lung disease in which inflammation causes narrowing of the airways, resulting in wheezing, coughing, shortness of breath and tightness in the chest.
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We have known for years that obese people are more likely than thinner people to develop certain types of asthma or to have increasing asthma symptoms.
According to the US Centers for Disease Control and Prevention, 38.8% of adults with asthma are obese, which is much higher than the rate of obesity in non-asthmatic adults, which increases to 26%. , 8%.
Of course, this could be due to the fact that asthma prevents some people from staying active … or maybe inactivity and overweight exert pressure on the body, causing an asthmatic response .
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