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Studies suggest that healthy people who take a daily aspirin to prevent heart attacks later can do more harm than good.
Aspirin – which dilutes blood – has been administered for decades to people diagnosed with heart disease to stop heart attacks and strokes.
But many healthy middle-aged people also consider pills as an "insurance policy" against heart problems.
A major new study, including data from more than 160,000 people, concludes that the risk of major internal bleeding significantly outweighs the benefits of aspirin in patients with no history of disease heart.
Aspirin, which dilutes the blood, is regularly administered to healthy people of middle age, to reduce the risk of heart problems
The review, led by experts from King's College London, reinforces the increasingly obvious evidence that aspirin should no longer be used for purposes of "primary prevention," the term designating the treatment of patients with no symptoms of heart problems.
The researchers found that in healthy people, the use of aspirin resulted in an 11% decrease in the risk of heart attack or stroke.
But the risk of bleeding has increased by 43%.
This means that 265 people should take aspirin for five years to prevent a single heart attack or stroke – but one in 210 would have significant bleeding.
Dr. Sean Zheng, a clinical cardiology clinical researcher at King's College London, said, "This study demonstrates that there is insufficient evidence to recommend systematic use of aspirin in preventing seizures. heart disease, stroke and cardiovascular death in people without cardiovascular disease. "
Can ASPIRIN REDUCE YOUR RISK OF CANCER?
Taking a quarter of an aspirin tablet a day could reduce the risk of bowel cancer by a fifth, concluded a large study in March 2016.
Harvard scientists have found that people of average age taking regular painkillers are less likely to be diagnosed with cancer, regardless of their nature.
They discovered that cheap pills, which cost less than 2 pence per tablet, are particularly effective at fighting digestive system cancers.
The most dramatic impact was observed on bowel cancer, people taking aspirin daily for six years having seen their risk drop by 19%.
The experts, who followed 136,000 people for 32 years, predicted that regular use of aspirin in the United States would prevent 30,000 tumors a year.
The team found that the situation was more complicated for diabetic patients, who are at higher risk for heart disease and who are often prescribed aspirin.
Among these patients, the risk of heart attack or stroke also decreased by 11% – and the risk of bleeding increased by 30%.
Dr. Zheng said, "There is more uncertainty about what should be done in patients at increased risk of cardiovascular disease and in diabetic patients.
"This study shows that although cardiovascular events can be reduced in these patients, these benefits are accompanied by an increased risk of major bleeding events.
"The use of aspirin requires a discussion between the patient and his doctor, knowing that potential potential cardiovascular benefits are weighed against the real risk of serious bleeding."
In the past, low-dose aspirin, which is very cheap, was often prescribed to healthy people, even in the middle ages, to reduce heart disease.
The guidelines issued by several professional health organizations between 2005 and 2008 have supported this position, recommending the routine use of aspirin in people aged 50 and older with type 2 diabetes or diabetes mellitus. hypertension.
Ten years ago, a series of major studies began to reveal the risk of significant bleeding, and the guidelines were changed to remove the formal recommendation, but many doctors still prescribe the drugs.
Experts are also worried about many "worried patients" taking the tablets without realizing the side effects that may include internal bleeding.
Professor Jeremy Pearson, deputy medical director of the British Heart Foundation, said: "Current recommendations do not recommend aspirin to people who are not already suffering from heart or circulatory diseases.
"Indeed, while aspirin reduces the risk of heart attack and stroke in these people, its benefits are outweighed by an increased risk of bleeding.
"If you have a heart attack, your doctor will usually prescribe a daily aspirin to prevent a second seizure. In this case, the reduced risk of a second life-threatening heart attack far outweighs the risk of side effects, such as bleeding.
"The risk of bleeding caused by aspirin will probably be different from one group of people to the other. Further research may well reveal subgroups of people where the benefits outweigh the risks, paving the way for personalized treatments. & # 39;
Jane Armitage, a professor at Oxford University, said: "The conclusion [in this paper] reinforces the message of these trials that, for healthy people, the small benefits of aspirin in preventing strokes and heart attacks are counterbalanced by an increased risk of serious bleeding.
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