Deep learning to improve immunotherapies against cancer and other diseases



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The T cell receptor, or TCR, is the component of the immune system that releases white blood cells to fight and try to kill infected, foreign, and cancerous cells.

Calling their open source package DeepTCR, the authors tell Johns Hopkins’ news division that the software uses supervised and unsupervised deep learning.

Unsupervised approaches “allow investigators to analyze their data in an exploratory fashion, where there may not be known immune exposures, while supervised approaches will allow investigators to take advantage of known exposures to enhance learning. models, ”says Johns Hopkins in an article. Release.

“As a result… DeepTCR will allow researchers to study the function of the immune response of T cells in basic and clinical sciences by identifying the patterns in the receptors that confer on the T cell the function of recognizing and killing pathological cells. “

The study is available in its entirety free of charge.

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