Exercise During Pregnancy Protects Offspring From Obesity

Orlando, Florida (April 7, 2019) – A new study found that offspring born from mice exercising during pregnancy were less likely to gain weight after consuming a high-fat diet later. Although previous studies have shown that exercise performed by obese women was beneficial for their offspring, this is the first study to demonstrate that the same is true when non-obese women exercise.

"Based on our findings, we recommend that women – whether they are obese or not – with diabetes – exercise regularly during pregnancy, as this improves the metabolic health of their children." said Jun Seok Son, a PhD student at Washington State University. conducted the study.

His will present these new findings at the annual meeting of the American Physiological Society at the 2019 meeting on Experimental Biology to be held April 6-9 in Orlando, Florida.

The researchers examined the offspring of mice who engaged in moderate-intensity physical activity for 60 minutes each morning of pregnancy. Offspring born from mice that did not exercise were used as a control group.

At weaning, the offspring of the exercising mice had an increase in brown adipose tissue protein levels relative to the control group. This type of fabric converts fat and sugar into heat. The researchers also observed higher body temperatures in the exercise group, indicating that their brown adipose tissue was more effective – or had superior thermogenic function – which was proven that it could prevent cancer. Obesity and metabolic problems.

After weaning, the offspring followed a high-fat diet for eight weeks. The mice in the exercise group not only gained less weight with the high-fat diet, but also exhibited fewer symptoms of metabolic diseases such as diabetes and fatty liver.

"Our data suggest that lack of exercise in healthy women during pregnancy can predispose their children to obesity and badociated metabolic diseases, including altering thermogenic function," said Son.

The researchers plan to conduct additional studies to better understand the biological mechanisms responsible for improving metabolic health in the children of mothers who have exercised.

Jun Seok Son will present this research on Sunday April 7th from 10:15 am to 12:15 pm. in the exhibition hall – West Hall B, Orange County Convention Center and Monday, April 8 at 4:30 pm in Room W311B (summary). Contact the media team for more information or to get a free pbad to attend the meeting.

###

Images and video available

About 2019 Experimental Biology

Experimental Biology is an annual meeting that attracts more than 14,000 scientists and exhibitors from five host companies and more than two dozen corporate guests. With a mission to share the latest scientific concepts and research results that shape clinical advances, the meeting provides an unprecedented opportunity for exchange between scientists from the United States and around the world representing dozens of scientific fields from the laboratory to translational or clinical research. http: // www.Experimental biology.org #expbio

About the American Physiological Society (APS)

APS is a non-profit organization dedicated to the promotion of education, scientific research and information dissemination in the physiological sciences. The company was founded in 1887 and today represents more than 10,500 members and publishes 14 peer-reviewed journals. http: // www.the-aps.org

You will find more news and fact sheets on: https: //www.EurekAlert.org /meetings /eb /2019 /writing/