Fast-acting psychedelic associated with improved depression / anxiety – ScienceDaily



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Johns Hopkins researchers have discovered that the use of synthetic psychedelic 5-methocy-N, N-dimethyltryptamine (5-MeO-DMT) seems to be badociated with unintended improvements in depression and depression. self-reported anxiety at a ceremony. 5-MeO-DMT is a psychedelic that is found in the venom of Bufo Alvarius toads, in various plant species, and can be produced by synthesis.

In a survey of 362 adults, about 80% of respondents reported an improvement in anxiety and depression after use. These improvements were related to more intense acute mystical effects during the 5-MeO-DMT experience, as well as increasingly important badessments of the personal significance and spiritual significance of the 5-MeO-DMT. # 39; s experience. Improvements were also related to stronger beliefs that experience contributes to sustainable well-being and life satisfaction. These results were published in The US newspaper on the abuse of drugs and alcohol.

One of the unique properties of 5-MeO-DMT is the rapid action and short duration of psychedelic effects compared to other psychedelics. "Research has shown that psychedelics in combination with psychotherapy help people with depression and anxiety, but psychedelic sessions typically require 7 to 8 hours per session, as psychedelics usually have a long duration of time. Action, "says Alan K. Davis, Ph.D., postdoctoral researcher at the Behavior Research Unit of the Johns Hopkins University School of Medicine. "Since 5-MeO-DMT acts quickly and lasts about 30 to 90 minutes, it could be much easier to use in addition to treatment, because current treatments usually involve a 60 to 90 minute session."

Last year, Davis published a study in Frontiers in Psychology this revealed that 5-MeO-DMT administered in a psychospiritual retreat produced comparable badessments of the mystical experience of a high-dose psilocybin session in the laboratory. Another Davis study published last year in The Journal of Psychopharmacology showed that the profile of 5-MeO-DMT had a safe use profile and a low risk to health and legal consequences.

"It is important to consider the short-term and long-term effects of 5-MeO-DMT, which may improve mood in general or be especially in people with clinically significant negative mood, "Davis said. "Whatever it is, this research is in its infancy and further research is needed in healthy volunteers."

The authors of this article were Alan K. Davis, Sara So and Roland R. Griffiths of Johns Hopkins, Rafael Lancelotta of the University of Wyoming, and Joseph P. Barsuglia of New School Research.

The study was funded by grants from the National Institute for Combating Alcohol Abuse (AA 007747) and the National Institute for Combating Drug Abuse (T32 DA007209, R01 DA003889).

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Material provided by Johns Hopkins Medicine. Note: Content can be changed for style and length.

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