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The risk of dementia was reduced by 32% in people with high genetic risk if they had followed healthway of life, compared to those who had ahealthy lifestyle, the study, published in the medical journal JAMA Sunday, found.
People at high genetic risk and ahealthy lifestyle were almost three times more likely to develop dementia than those with low genetic risk who also lived healththere is.
"Our results are exciting because they show that we can act to compensate for our genetic risk of dementia," said Elzbieta Kuzma, a researcher at the British University of Exeter, who led the study.
Dementia – a disease that spends the brain – affects about 50 million people worldwide, with nearly 10 million new cases a year – a figure that is expected to triple by 2050, according to the world Health Organization.
The Kuzma team badyzed data from nearly 197,000 adults of European descent aged 60 and over. They found 1,769 cases of dementia over an eight-year follow-up period and grouped them into people at high, medium and low risk for dementia.
To badess lifestyle, researchers examined the diet, physical activity, smoking and alcohol consumption reported by participants.
Non-smokers who exercised regularly and had a good diet with moderate alcohol consumption were consideredhealththeir lifestyles – and it was found that these people had reduced their risk, whether they belong to a high, medium or low genetic risk group.
David Llewellyn, also from Exeter University, said the results of his research carried an important message that undermined what he described as "a fatalistic view of dementia".
"Some people believe that it is inevitable that they develop dementia because of their genetics," he said. "(But) you may be able to significantly reduce your risk of dementia by living healthy lifestyle ".
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