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Pulmonary hypertension (PAH) is a life-threatening progressive disease, which means that you have high blood pressure in the arteries that go from the heart to the lungs. PAH is a rare complication of lupus and affects less than 1% of Caucasians with systemic lupus erythematosus (SLE); However, current literature suggests that the incidence and survival rates of Asians with lupus may be different from those in Western countries.
In an effort to better understand the incidence and survival rate of Asians with lupus and PAH, researchers badyzed data from a retrospective cohort study. The cohort included 15,783 people with lupus, of whom only 336 developed PAH. Of these, the majority (70%) developed PAH within 5 years of the diagnosis of SLE. Systemic arterial hypertension (high blood pressure) and bad (female) were predictive factors for PAH, and the risk of death was much higher in patients with PAH than in those without PAH.
The study showed that the overall survival rate of a person suffering from both lupus and PAH is worse in Asian countries compared to Western countries; more research is needed to understand this difference. In addition, the results showed that systemic hypertension could be a predictor of PAH in Asians. Investigators recommend that physicians be more aware of PAH in people with lupus and systemic hypertension. Discover how lupus affects the heart and circulation.
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