Lab test could help develop easy-to-swallow medications



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Scientists have developed an innovative test that could help develop easy-to-swallow medicines for children and the elderly.

Researchers at the University of Surrey and the University of College London have developed a test to determine the extent to which small, multiple particles can facilitate the pbadage of medication from the mouth to the throat and body.

The new test allows scientists to easily select different compositions of the vector fluid and the concentration of particles to facilitate swallowing.

Dr. Marco Ramaioli, a senior lecturer at the University of Surrey and co-author of the study, said: "Many young children and elderly people are struggling to swallow conventional tablets, which prevents them from completing the drug treatment. We hope this in vitro This method, combined with sensory testing, will help develop new drugs that could improve the lives of many people around the world. "

Professor Catherine Tuleu of UCL School of Pharmacy said, "It is exciting to see progress in designing age-appropriate drugs, such as multiparticulate systems, but successful therapeutic outcomes are based on the development of appropriate administration vehicles. "

Dr. Mine Orlu, also from the UCL School of Pharmacy, added, "The availability of predictive models to characterize promising formulation platforms early on in the development of a drug is essential for the production of easier drugs to take for patients with different swallowing abilities.

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