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Low Line: The proportion of liver transplants in the United States for alcohol-related liver disease increased between 2002 and 2016, with this increase being largely badociated with a decrease in the number of liver transplants for infection with the virus. of hepatitis C due to antiviral treatment. This observational study used data from the Unified Network for Organ Sharing for all liver transplants over the 15-year period. The national study group included almost 33,000 patients, including 9,438 patients diagnosed with alcohol-related liver disease. The results of the study suggest that five-year survival after transplantation was lower in patients with alcohol-related liver disease. The authors suggest that the increase in the number of liver transplants for alcohol-related liver disease may be related to the change in attitude regarding the duration of sobriety required for a transplant. The study is based on the data of the register, all conclusions are badociative and not causal. Regional differences suggest different policies for liver transplantation for liver disease badociated with alcohol.
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authors: Norah A. Terrault, M.D., of the University of California at San Francisco, and co-authors
(doi: 10.1001 / jamainternmed.2018.6536)
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