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Category: News, women's health published by sana published: March 24, 2019 at 7:30 pm Eastern Time Update: March 24, 2019 at 7:30 pm Eastern Time
New York: Researchers have shown in an animal study that exposure to low light at night could contribute to the spread of bad cancer to the bones.
When bad cancer spreads, it often affects the bones, causes acute pain and weakens them. "To date, no one has reported that exposure to subdued light at night induces circadian disturbances, which increases the spread of metastatic bad cancer," said Muralidharan Anbalagan, badistant professor at the University of Toronto. Tulane University of New Orleans.
The results were presented at the annual ENDO 2019 meeting organized by the Endocrine Society in New Orleans.
For the preliminary study, the team created a mouse model of metastatic bad cancer. They injected into the tibia (shin) of female mice positive human estrogen receptor bad cancer cells, which have a low propensity to grow in the bones.
Like humans, mice produced a strong circadian melatonin nocturnal signal, which has been shown to produce strong anticancer actions and promote sleep.
While one group of mice was in light 12 hours a day, the other group of three mice was in the dark for 12 hours. Another group spent 12 hours in the light, followed by 12 hours in the dark at night.
X-rays showed that mice exposed to a light or dimly lit cycle had much larger tumors and larger bone lesions than mice kept in a standard light / dark cycle, he noted.
"Our research has highlighted the importance of an anticancer signal of intact nocturnal circadian melatonin in suppressing the growth of metastatic-osseous bad tumors," Anbalagan said.
Source: IANS
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