[ad_1]
New York, March 25 (IANS): Exposure to low-light evening can contribute to the spread of bad cancer to bone, researchers have shown in an animal study.
When bad cancer spreads, it often affects the bones, causes acute pain and weakens them. "To date, no one has reported that low-light nocturnal exposure induces circadian disturbances, which increase the spread of metastatic bad cancer of the bones," said Muralidharan Anbalagan, badistant professor at Tulane University of Toronto. New Orleans.
The results were presented at ENDO 2019, the annual meeting of the Endocrine Society in New Orleans.
For the preliminary study, the team created a mouse model of metastatic bad cancer. They injected into the tibia (shin) of female mice positive human estrogen receptor bad cancer cells, which have a low propensity to grow in the bones.
Like humans, mice produced a strong circadian melatonin nocturnal signal, which has been shown to produce strong anticancer actions and promote sleep.
While one group of mice was in light 12 hours a day, the other group of three mice was in the dark for 12 hours. Another group spent 12 hours in the light, followed by 12 hours in the dark at night.
X-rays showed that mice exposed to a light or dimly lit cycle had much larger tumors and larger bone lesions than mice kept in a standard light / dark cycle, he noted.
"Our research has highlighted the importance of an anticancer signal of intact nocturnal circadian melatonin in suppressing metastatic bad tumor growth," Anbalagan said.
[ad_2]
Source link
