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THURSDAY, Jan. 14, 2021 (HealthDay News) – Patients with type 2 diabetes who adhere to a low-carb diet (LCD) for six months may experience higher rates of diabetes remission, according to a review published online on the 13th january in BMJ.
Joshua Z. Goldenberg, Ph.D., of Texas A&M University at College Station, and his colleagues conducted a systematic review and meta-analysis to examine the efficacy and safety of LCD and highly LCD displays (VLCDs ) for people with type 2 diabetes. Data were included from 23 trials with 1357 participants.
Researchers found that compared to control diets, at six months, LCDs achieved higher rates of diabetes remission (defined as hemoglobin A1c [HbA1c] <6.5 percent; 57 versus 31 percent; risk difference, 0.32). When an HbA1c remission definition of <6.5 percent without drug was used, smaller and non-significant effect sizes were observed. Data on 12-month remission were scarce, ranging from a small effect to an insignificant increase in diabetes risk. At six months, there were significant, clinically important improvements in weight loss, triglycerides, and insulin sensitivity, which decreased at 12 months. VLCDs appeared to be less effective than less restrictive LCD screens; this effect is explained by membership in the plan. No significant difference was observed in the quality of life at six months; however, a clinically significant, but not statistically significant, worsening was observed at 12 months.
“Clinicians might consider short-term LCD screens for the management of type 2 diabetes, while actively monitoring and adjusting diabetes medications as needed,” the authors write.
An author has revealed financial ties to Texas A&M AgriLife Research.
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