NIH Grant of $ 4.23 Million to Support the Development of the Cleveland Alzheimer's Disease Research Center



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The National Institute of Aging National Institutes of Health (NIH) awarded a $ 4.23 million grant for the establishment of the Cleveland Research Center on Alzheimer's Disease. This award, lasting two years, will support the development of a multi-agency collaboration to accelerate research on Alzheimer's disease and related dementias.

The Cleveland Alzheimer's Disease Research Center, led by James Leverenz, MD, of the Cleveland Clinic, will be one of 31 centers of excellence in disease research. Alzheimer's funded by the NIH in the country and being part of the program of Alzheimer's disease research centers. The new multi-institutional center – the first in Ohio – brings together the best researchers and clinicians from Case Western Reserve University, Cleveland Clinic, Louis Stokes Cleveland VA Medical Center, MetroHealth and University Hospitals.

The Alzheimer's Disease Research Centers program is a national network of researchers and clinicians working in leading medical institutions in the United States. Researchers at these centers are employing to translate advances in research into improved diagnosis and care for people with Alzheimer's disease, as well as finding a way to heal and eventually to prevent the disease.

More than 5.3 million Americans suffer from Alzheimer's disease. This number is expected to almost triple by 2050.

"The Cleveland Alzheimer's Disease Research Center will bring together the considerable skills of the medical and academic communities of northeastern Ohio to focus on one of the largest health care crises in the world. health that our country and the state of Ohio are facing, "said Dr. Leverenz, director of the Cleveland Clinic Lou Ruvo Center for Brain Health in Cleveland. "The center will create a solid infrastructure to accelerate research to better understand and treat Alzheimer's disease and related dementias." As a multi-facility collaboration with a large patient population and in-depth research and treatment expertise of dementia, we are particularly well placed center-impact. "

"This is an exciting development for Cleveland and doctors working in multiple hospitals can do great things," said Alan Lerner, MD, director of the Brain Health and Memory Center at University Hospitals Cleveland Medical Center. "Our goal is to advance research and ultimately improve the lives of those affected by this devastating disease."

The new center will support a wide range of studies while informing scientists, health professionals and the public about the causes and treatment of dementia. It will have eight hearts led by experts from participating institutions: Administration (Dr. Leverenz), biomarkers (Lynn Bekris, Ph.D., Cleveland Clinic); Clinic (Dr. Lerner, UH / CWRU); Data Management and Statistics (Jonathan Haines, Ph.D., CWRU); Neuropathology (Mark Cohen, M.D., and Brian Appleby, M.D., CWRU / UH); Outreach, Recruitment and Engagement (Martha Sajatovic, MD, UH / CWRU), Research Training (Xiongwei Zhu, PhD, CWRU) and Translational Therapeutic Therapy (Andrew Pieper, MD, Ph.D., Harrington Discovery Institute at UH / VA)).

"Our team is eager to contribute to the new center, providing statistical and computer expertise leveraging our vast experience in conducting large-scale studies integrating" omic "and clinical data on tens of thousands of lives "said Dr. Haines, president of Case Department of Demographic and Quantitative Health Sciences Western Reserve. "Alzheimer's disease affects all ethnicities and all socioeconomic clbades and represents a huge burden in northeastern Ohio.Our diverse urban and rural population, badociated with genetic and Detailed clinical, and the wealth of additional data from electronic medical records, means this new Cleveland Center is uniquely positioned to make a significant contribution to the national research agenda. "

The center's particular areas of interest will be atypical Alzheimer's disease (for example, "rapidly progressive"), Lewy body dementia, healthy individuals at risk of developing dementia, and underserved populations. In addition to community outreach, the center will develop an infrastructure and support for promising new researchers, and will promote the translation of lab results into new treatments for these devastating diseases.

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