People who ‘can’t fit in the jeans they wore at age 21’ are at risk of developing diabetes | Diabetes



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People are at risk of developing type 2 diabetes if they can’t fit into the jeans they wore when they were 21, according to one of the world’s leading experts on the disease.

And if people found out that they couldn’t fit into the same size pants anymore, then they were “wearing too much fat,” said Professor Roy Taylor of Newcastle University.

Taylor was presenting data at the European Association for the Study of Diabetes annual conference on a first study that found that normal-weight people with type 2 diabetes could “go into remission” by losing weight.

Eight out of 12 people managed to “get rid” of their disease by losing 10-15% of their body weight.

The participants, who suffered from type 2 diabetes despite having a “normal” body mass index (BMI), were successful in reducing fat levels in the liver and pancreas, and the activity of insulin-producing cells in the liver. pancreas was found to be restored.

Taylor, the lead researcher, said: “Doctors tend to assume that type 2 diabetes has a different cause in those who are not overweight. What we have shown is that if those of normal weight lose 10-15% of their weight, they have a very good chance of getting rid of their diabetes.

The participants, who had an average BMI of 24.5, followed a weight loss program that included a low-calorie liquid diet for two weeks – where each day they consumed just 800 calories per day through soups and shakes.

They completed three rounds of this program until they lost 10-15% of their body weight.

Once weight loss was achieved, scans showed a reduction in fat in the liver and eight of the 12 participants saw their type 2 diabetes go into remission, which was defined as blood sugar and patient control. no longer needing medication.

Taylor said the results, although preliminary, “show very clearly that diabetes is not caused by obesity but by being too heavy on your own body.”

He added: “If you can’t put on the same size pants now, you are wearing too much fat and therefore you are at risk of developing type 2 diabetes even if you are not overweight.

Dr Lucy Chambers, head of research communications at Diabetes UK, which funded the study, said she welcomed the results but warned they were early, with full results expected in 2022.

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