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Yes statistics It must be believed that in 2016 alone, there were 216 million cases of malaria in 91 countries in total. In addition, in the United States of America, the Centers for Disease Control (CDC) report a total of 1700 annual cases of malaria.
It has also been found that the majority of cases occur in individuals traveling to these countries. countries where it is more common to contract malaria.
Malaria can easily be considered a deadly disease. As a rule, it is transmitted when an infected Anopheles mosquito bites an individual.
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These infected mosquitoes also carry the parasite Plasmodium. As soon as this mosquito stings us, the parasite Plasmodium is released directly into our bloodstream.
Moreover, once these parasites are in our body, things become even more dangerous as they go directly to the liver – a place where they mature. Then, after a few days, these mature parasites re-enter the bloodstream and then begin to infect our red blood cells.
The parasites begin to multiply in red blood cells within 48 to 72 hours and cause the infected cells to burst into the bloodstream. Subsequently, these parasites continue their work by infecting red blood cells. This eventually results in symptoms that appear in a cycle of 2-3 days at a time.
What is the first sign of malaria?
A malaria attack usually starts with chills and chills, followed by a high fever. A person then usually experiences heavy perspiration, after which it is likely to return to a normal temperature.
the Signs and symptoms Malaria cases usually start a few weeks after an infected Anopheles mosquito has bitten a person.
It should also be noted that in the beginning, malaria is very worrying. like the flu as victims experience symptoms such as tiredness, high fever, hot and cold patches, and aches and pains The symptoms of malaria are also very similar to those of yellow fever, a viral disease.
These symptoms and signs may be somewhat nonspecific in children, which may delay the diagnosis. Other symptoms include nausea, headache, weakness and chills or tremors.
Can you cure malaria completely and is it curable?
Malaria can be treated given the good administration of drugs. In such a scenario, it is possible to rid the body of all malaria parasites and cure the disease.
That said, it is possible that the disease continues to infect the red blood cells if the proper treatment is not administered or if the wrong drugs are used to treat the disease. In addition, the duration of malaria treatment depends on the type of malaria that an individual has contracted.
If not treated quickly, malaria can last for several months and can prove fatal.
What is the best treatment available for malaria?
According to studies published in The New England Medical Journal, there is a brand new single-dose drug that can prevent the relapse of malaria. This miracle drug is known as tafenoquine, and research has shown that it can be a drug anti-relapse drug for patients infected with the parasite Plasmodium vivax malaria.
In addition, this medication has been shown to be safe and effective.
The Food and Drug Administration (FDA) and the Australian Therapeutic Goods Administration approved tafenoquine in 2018. This drug has become the first drug to use the malaria parasite for more than 60 years.
In January of this year, new discoveries about another antimalarial drug called artemisinin. This product is derived from the flowers and leaves of Artemisia annua, which is the annual sagebrush.
This medicine has been used traditionally as a Chinese healing medicine for centuries. Tu Youyou, a Chinese researcher has tested the effectiveness for which he even received the Nobel Prize.
Generally, artemisinin, as well as its semi-synthetic derivatives, are called "artemisinins". These are used to treat malaria as well as other tropical infectious diseases.
This drug is recognized for its effectiveness in the treatment of malaria because its molecules affect the activation of multiple cellular processes in humans. In addition to this, it has also been discovered that artemisinins could be a cure for other diseases such as certain types of cancer, diabetes and even neurological diseases such as schizophrenia and Alzheimer's disease.
Apart from these drugs, there are a lot of treatments and drugs which are administered to cure malaria. Drugs such as quinine, chloroquine, tetracycline, mefloquine, etc. are also used for the treatment of malaria because they are very active against different forms of parasites in the blood.
In addition, tafenoquine and primaquine are hyperactive drugs against dormant parasites. As a result, they have been shown to be effective in preventing relapse.
That said, the CDC recommends not taking these two drugs orally or otherwise in people with glucose-6-phosphate dehydrogenase deficiency or in pregnant women.
It is also relevant to note here that the treatment of malaria depends on various factors such as the species or type of parasite infecting, pregnancy, drug allergies, any disease or disease that accompanies it, and the clinical status of the disease. patient. In addition, the precise area where the patient has been infected as well as their drug resistance status also play a major role in determining the treatment that will be administered to a patient.
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According to the conditions mentioned above, the treatment of malaria can be administered radically or restrictively.
Final words
Although malaria is still considered a deadly disease, we have come a long way to effectively treat its symptoms. A multitude of new treatments and medications have proven beneficial in the treatment of malaria. However, early diagnosis and timely administration of appropriate treatment, as well as further research, are essential for the definitive cure of malaria.
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