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Paternal smoking, in addition to maternal second-hand smoke, increases the risk of conbad heart defects in offspring, according to findings published in the European Journal of Preventive Cardiology.
The researchers sought to evaluate the risk of conbad heart defects badociated with active and pbadive smoking of the mother and paternal smoking.
"Smoking is a teratogenic agent, which means that it can cause developmental malformations", Jiabi Qin, MD, PhD, of the Department of Epidemiology and Health Statistics of the Xiangya School of Public Health at Central South University, said in a press release. "The badociation between future parents who smoke and the risk of conbad heart defects has more and more attention with the growing number of smokers of childbearing age."
Researchers badyzed seven electronic databases until June 2018.
They identified 125 studies with 137,574 cases of conbad heart defects in 8,770,837 participants.
According to the study, paternal active smoking (RR = 1.74, 95 CI, 1.48-2.06) and maternal pbadive smoking (RR = 2.24, 95% CI, 1.81-2.77 ) were significantly badociated with the risk of conbad heart defects in children. Active maternal smoking also had a significant badociation (RR = 1.25, 95% CI, 1.16-1.34) with the risk of conbad heart defects.
Paternal smoking, in addition to maternal second-hand smoke, increases the risk of conbad heart defects in offspring, according to findings published in the European Journal of Preventive Cardiology.
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Active smoking in the mother was significantly badociated with the risk of atrial septal malformation (RR = 1.27, 95% CI, 1.02-1.59) and obstruction of the right ventricular tract ( RR = 1.43, 95% CI, 1.04-1.97) that a sensitivity badysis yielded consistent results.
Preventing parental smoking during pregnancy is a priority to reduce the risk of conbad heart defects, they wrote.
"Physicians and primary health care professionals need to do more to educate and educate prospective parents about the potential dangers of smoking for their unborn child," Qin said in the statement. – by Earl Holland Jr.
Disclosures: The authors do not report any relevant financial information.
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