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Prescription drugs given to help treat prostate hypertrophy could increase the risk of type 2 diabetes, according to a new study.
A study of 55,000 men was conducted by the University of Edinburgh and University College London (UCL) over an 11-year period.
They examined the impact of taking 5-alpha-reductase inhibitors on the health of all participants. They found evidence suggesting that drugs increased the risk of type 2 diabetes by one-third.
The 5-alpha-reductase inhibitor drug is usually given to men who have enlarged prostate glands. The researchers pointed out that they could still safely take, but those recommended might need an extra checkup to discuss their medications.
"These findings will be particularly important for medical screening in older men who are already at a higher risk for type 2 diabetes. We will now continue our studies to better understand long-term outcomes to better identify the most likely patients." exposed to risk, "said Professor Ruth Andrew, senior author of the Center for Cardiovascular Sciences University / British Heart Foundation of the University of Edinburgh.
Dr. Li Wei, badociate professor at UCL School of Pharmacy and first author of the study, added, "By studying real data from different ethnic groups in the United Kingdom and Taiwan, we found that men treated with dutasteride or finasteride for benign prostatic hyperplasia (BPH) have an increased risk of developing diabetes by approximately 30%.
"It shows how important it is to use regularly collected health data to identify meaningful clinical links, and it is important for all patients to be aware of the risks and benefits of their medications. Men should be warned of the increased risk of diabetes if they take these particular medications for BPH, and should talk to their doctor if they are concerned. "
The results were published in the British Medical Journal.
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