[ad_1]
According to a new study, women who develop diabetes during pregnancy but who are not diagnosed are much more likely to have a stillbirth.
The study, led by the University of Leeds and the University of Manchester, found that the risk of stillbirths was four times higher in women who had signs of gestational diabetes but were undiagnosed.
However, with appropriate screening and diagnosis, the increased risk of stillbirth has disappeared.
Funded by charities Action Medical Research, Cure Kids, Sands and Tommy's, the study compared the symptoms and care of 291 women who had a stillbirth to 733 similar women who did not have unbadisted delivery in 41 maternity homes in England.
The researchers found that in all women with high blood glucose measured after a fasting period, they were on average twice as likely to be born dead as women without any disease.
The increased risk was likely due to missed diagnoses and the lack of subsequent care of many women, although the results show badociation only and can not provide certainty about cause and effect.
The new research was published in BJOG: an international journal of obstetrics and gynecology.
Dr. Tomasina Stacey, who led the study at the University of Leeds and now works at Huddersfield University, said: "There is good news and bad news.The good news is that women with Gestational diabetes have no increased risk of stillbirth guidelines are followed for screening, diagnosis and management.The bad news is that they are not always followed and that some women are therefore at an avoidable risk. "
According to recent figures, about 5% of British women have gestational diabetes during pregnancy.
The National Institute for Care Excellence (NICE) recommends that all women at high risk of gestational diabetes be screened for blood, including women with high body mbad index (BMI> 30). ), South Asians or the United States. Black Caribbean ethnic groups.
Only 74.3% of participating women with a high BMI and 74.7% of participating women belonging to South Asian or Black Caribbean ethnic groups were screened.
On average, women at higher risk of gestational diabetes who were not screened according to NICE guidelines also had a higher risk of stillbirths.
Professor Alexander Heazell, co-author of the University of Manchester and Clinical Director of the Tommy & # 39; s Stillbirth Research Center, said: "It is unclear why some women have escaped the screening or diagnosis of gestational diabetes, but this needs to be improved.
"Gestational diabetes can lead to serious complications during pregnancy, and it is important to detect all women with symptoms so that they can receive appropriate care and support."
In 2015, NICE has raised the diagnostic threshold for gestational diabetes to a fasting plasma glucose concentration (measured when blood glucose is measured after fasting) in excess of 5.6 mmol / L. In the United States, the threshold is of 5.1 mmol / L and the appropriate level of diagnosis is highly controversial worldwide.
The present study found little evidence to support one threshold over another, but rather that the risk of stillbirth increased steadily with increasing glucose concentration.
Dr. Stacey, who also works in Calderdale and the Huddersfield NHS Foundation Trust, added: "There is no blood sugar level where the risk suddenly increases, so the choice of the appropriate threshold for diagnosis is based more on pragmatism and research. the right balance between risk and resources and avoiding over-medicalization Our study shows that current NICE guidelines can be effective, but only if they are followed. "
According to recent figures from MBBRACE-UK, about four out of every 1,000 births in the UK result in a stillbirth.
Commenting on the research, Dr. Edward Morris, Vice President of Clinical Quality for the Royal College of Obstetricians and Gynecologists, said, "Women with gestational diabetes are more likely to have stillbirths, but with surveillance, care and Adequate treatment, this risk can be managed so that women can maximize their chances of having a healthy pregnancy and childbirth.
"Maternity units should follow NICE's clinical guidelines to ensure that women are diagnosed and supported to avoid complications and to ensure the best possible outcomes."
This study is unique in separating the adverse biological effects of blood glucose on the benefits of diagnosis, which generally leads to better care and better disease management.
Dr. Peter Tennant, co-author of the University of Leeds and the Alan Turing Institute, explained why this is so important. He said: "The real impact of gestational diabetes is the subject of much debate. It is difficult to spend so much time and money on the screening, diagnosis and care of these mothers. But most women with diabetes currently receiving good care, seems to really help.
"It's only when you look at women who are not screened or diagnosed appropriately that the full impact of gestational diabetes becomes clear."
The research project came out of a summit on death at birth in 2011 and was created with the help of more than 550 parents and members of the public. It was designed by and for parents to maximize the positive impact it could have on society.
###
Notes to editors
For any interview requests, please contact Simon Moore, press officer at the University of Leeds, at 0113 34 38059 or at [email protected].
The document is entitled "Gestational diabetes and risk of late stillbirth: a case-control study conducted in England, in the United Kingdom". It will be available online at the following address: https: /
More information on gestational diabetes, including symptoms, treatment and management can be found on the Diabetes UK website.
University of Leeds
The University of Leeds is one of the largest higher education institutions in the UK, with more than 38,000 students from more than 150 different countries, and a member of the Russell Group of Universities with strong research intensity. The University plays an important role in the Turing Institutes, Rosalind Franklin and Royce.
According to the 2014 Research Excellence Framework, we are one of the top ten universities in the UK for research and impact in the UK, and we figure in the top 100 of the QS World Ranking 2019 Universities
In 2017, the government's Gold Teaching Excellence Framework awarded the Gold Award, recognizing its always outstanding "teaching and learning" offerings. Twenty-six of our scholars have received national scholarships – more than any other institution in England, Northern Ireland, and Wales – reflecting the excellence of our teaching. http: // www.
Follow the University of Leeds or contact us on Twitter: Twitter Facebook LinkedIn Instagram
Source link
