Stress: Do you strain your way to cancer? Experts associate negative emotions with illness

BEIJING: Chinese researchers have revealed the mechanism by which chronic stress promotes the development of bad cancer by informing the future clinical treatment of cancer.

Cancer patients often suffer from negative emotions such as anxiety, hopelessness and fear, risk factors that facilitate tumor growth and promote cancer progression. However, the specific mechanisms of how chronic stress affects cancer development are still unknown.

Researchers from the Dalian Medical University in China discovered that chronic stress could increase epinephrine levels, thereby improving lactate dehydrogenase A (LDHA) and promoting stem cells resembling bad cancer. bad, reported Xinhua.

With the help of a screening of drugs targeting LDHA, they discovered that vitamin C reversed the stress-like chronic stem cancer-like phenotype.

This study demonstrates the critical importance of psychological factors in promoting stem-like properties in bad cancer cells and is a promising therapeutic approach for bad cancer, according to Liu Qiang, a senior researcher at the university school.

"Vitamin C, a cholesterol-lowering agent (LDHA), may be a potential approach in the fight against stress-related bad cancer," Qiang said in an article in the Journal of Clinical Investigation.

His team is engaged in the dynamic regulation of cancer stem cell research as well as in the mechanism of psychosocial behavior affecting the development of the tumor.

Qiang noted that patients with bad cancer, ovarian cancer and stomach often had negative emotions, which accelerated the development of their own tumors.

"It is necessary to monitor their chronic stress comprehensively by conducting psychological badessments and performing blood tests including epinephrine levels," Qiang said.