The discovery of proteins linked to several cancers could be beneficial to the development of a treatment: study – Xinhua

LONDON, Jan. 23 (Xinhua) – A specific protein has been badociated with aggressive cancers of the bad, colorectal cancer and ovarian, and the researchers believe that these findings could be used to improve the diagnosis and development of treatments, according to a study published Wednesday by the London-based Cancer Institute (ICR).

An ICR team discovered that Dickkopf-3 (DKK3) protein in cancer-badociated fibroblasts promotes growth and spread of the tumor. DKK3 protein is known to have the ability to activate the proteins involved in signaling pathways that promote tumor progression.

"This study found that DKK3 protein, unlike other DKK family proteins, promotes tumor growth and development, leading to more aggressive cancers of the bad, colon and ovaries," he said. said Dr. Fernando Calvo, head of research at the ICR. .

These results suggest that the discovery of drugs blocking the action of DKK3 could have a strong therapeutic potential in the treatment of more aggressive cancers, according to the study.

"The next step is to use the information from this study to develop drugs that target DKK3 to prevent its pro-cancer signaling, and to determine whether they have therapeutic benefit," Calvo said.