[ad_1]
WASHINGTON: A study says that women who take antibiotics for a long time are at increased risk of heart attack or stroke.
The study, published in the European Heart Journal, found that women aged 60 or older taking antibiotics for two months or more had the greatest risk of cardiovascular disease, but prolonged use of these antibiotics was also badociated with increased risk if age (40-59 years).
The researchers found no increased risk of antibiotic use in young adults aged 20 to 39 years.
The possible reason why the use of antibiotics is linked to an increased risk of cardiovascular disease is that antibiotics alter the balance of the microenvironment in the intestine, researchers said.
"The use of antibiotics is the most determining factor in altering the balance of microorganisms in the intestine. Previous studies have shown a link between alterations in the intestine. microbiotic environment in the intestine and inflammation and narrowing of blood vessels, strokes and heart disease, "said Lu Qi, director of Tulane University in the United States.
The researchers studied 36,429 women who participated in the Nurses' Health Study, which has been under way in the United States since 1976. This study examined data from 2004 to June 2012.
In 2004, women were aged 60 or older and were asked about their use of antibiotics when they were young (20 to 39 years old), of average age (40 to 59 years old) or older (60 years old and over).
The researchers clbadified them into four groups: those who had never taken antibiotics, those who had taken them for less than 15 days, 15 days to two months, or for two months or more.
During an average follow-up period of nearly eight years, during which women continued to complete questionnaires every two years, 1,056 participants developed cardiovascular disease.
The researchers found that women who used antibiotics for a period of two months or more at the end of their adult lives had a 32% increased risk of developing cardiovascular disease compared to women who did not use it.
Women who took antibiotics for more than two months in the middle age had an increased risk of 28% compared to women who did not take antibiotics.
These results mean that among women taking antibiotics for two months or more at the end of adulthood, six out of every 1,000 women would develop cardiovascular disease, compared to three out of every 1,000 women who did not have cardiovascular disease. not taken antibiotics.
"In studying the duration of the use of antibiotics at different stages of adulthood, we found a link between long-term use at middle and later ages and a increased risk of stroke and heart disease over the next eight years, "said Yoriko Heianza, a university researcher at Tulane University
"This is an observational study and therefore can not show that antibiotics are causing heart disease and stroke, but simply that there is a link between them, "said Qi Qi.
"It is possible that women who reported increased use of antibiotics would be sicker in some other way that we could not measure, or other factors could affect the results." that we have not been able to take into account, "he said.
"Our study suggests that antibiotics should only be used when they are absolutely necessary.In view of potentially cumulative adverse effects, the better it is, the less antibiotics should be used," he said. -he adds.
[ad_2]
The study, published in the European Heart Journal, found that women aged 60 or older taking antibiotics for two months or more had the greatest risk of cardiovascular disease, but prolonged use of these antibiotics was also badociated with increased risk if age (40-59 years).
The researchers found no increased risk of antibiotic use in young adults aged 20 to 39 years.
The possible reason why the use of antibiotics is linked to an increased risk of cardiovascular disease is that antibiotics alter the balance of the microenvironment in the intestine, researchers said.
"The use of antibiotics is the most determining factor in altering the balance of microorganisms in the intestine. Previous studies have shown a link between alterations in the intestine. microbiotic environment in the intestine and inflammation and narrowing of blood vessels, strokes and heart disease, "said Lu Qi, director of Tulane University in the United States.
The researchers studied 36,429 women who participated in the Nurses' Health Study, which has been under way in the United States since 1976. This study examined data from 2004 to June 2012.
In 2004, women were aged 60 or older and were asked about their use of antibiotics when they were young (20 to 39 years old), of average age (40 to 59 years old) or older (60 years old and over).
The researchers clbadified them into four groups: those who had never taken antibiotics, those who had taken them for less than 15 days, 15 days to two months, or for two months or more.
During an average follow-up period of nearly eight years, during which women continued to complete questionnaires every two years, 1,056 participants developed cardiovascular disease.
The researchers found that women who used antibiotics for a period of two months or more at the end of their adult lives had a 32% increased risk of developing cardiovascular disease compared to women who did not use it.
Women who took antibiotics for more than two months in the middle age had an increased risk of 28% compared to women who did not take antibiotics.
These results mean that among women taking antibiotics for two months or more at the end of adulthood, six out of every 1,000 women would develop cardiovascular disease, compared to three out of every 1,000 women who did not have cardiovascular disease. not taken antibiotics.
"In studying the duration of the use of antibiotics at different stages of adulthood, we found a link between long-term use at middle and later ages and a increased risk of stroke and heart disease over the next eight years, "said Yoriko Heianza, a university researcher at Tulane University
"This is an observational study and therefore can not show that antibiotics are causing heart disease and stroke, but simply that there is a link between them, "said Qi Qi.
"It is possible that women who reported increased use of antibiotics would be sicker in some other way that we could not measure, or other factors could affect the results." that we have not been able to take into account, "he said.
"Our study suggests that antibiotics should only be used when they are absolutely necessary.In view of potentially cumulative adverse effects, the better it is, the less antibiotics should be used," he said. -he adds.
#ElectionsWithTimes
Source link
