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There are two main causes of vitamin B12 deficiency: pernicious anemia and diet.
In the first case, your immune system destroys healthy cells in your stomach, preventing your body from absorbing the vitamin from the supplement and from the foods you take.
The second is due to insufficient intake of vitamin B12 through the diet. This could be because you are not eating enough foods rich in vitamin B12, or you are a vegan or vegetarian.
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