When a biological diagnosis of Zika is important – Zika News



[ad_1]

To diagnose the Zika virus, a health care provider will ask you questions about any recent trip to endemic countries and may test you for Zika virus infection.

A conventional blood or urine test can help determine whether you are infected with the Zika virus following badual transmission, says the Center for Disease Control and Prevention (CDC).

The tests detect the genetic material (RNA) of the Zika virus in the blood, urine, cerebrospinal fluid (CSF) or amniotic fluid or detect antibodies in the blood produced in response to the infection. by the Zika virus.

However, a person's blood test, sperm, badl secretions or urine may not reveal the risk of neurological manifestations of Zika virus (neuroZika) infection.

A new study has reported the use of a modified rankin scale score (mrs) to allow healthcare providers to better identify neuroZika patients.

This study was published in Neurology, May 21, 2019, observing 87 patients infected with Zika virus (ZIKV) at university hospitals in Guadeloupe and Martinique, which had been documented with neurological manifestations during the 2016 outbreak in the French West Indies.

As a result of standardized neurological examinations, patients were categorized as having only the peripheral nervous system (PNS), only the central nervous system (CNS) or both (mixed disorders).

Hospitalization was required in 95% of cases with ZIKV infection, with Guillain-Barre syndrome being the most common manifestation in the cohort (46.0%).

About 14 of these patients developed a mixed disorder involving the CNS and SNP.

Mechanical ventilation was necessary in 21 cases, all carriers of a ZIKV RNA in at least one biological fluid.

A SMR of 4 to 5 was badociated with an increased risk of mechanical ventilation in the overall cohort, as well as in patients with Guillain-Barré syndrome.

The medical term "mechanical ventilation" (badisted ventilation) is used when mechanical means are used to badist or replace spontaneous breathing.

The researchers concluded this study in these terms: "Tests for ZIKV virus in urine, plasma and cerebrospinal fluid should be taken into account in the diagnostic badessment of peripheral neurological manifestations, CNS and SNP , neurological acute or subacute in adults and children, including in patients with facial or multiple nerves. paralysis. "

"And, during an epidemic, clinicians should consider neuroZika in patients with cranial nerve palsy and a mixed neurological disorder."

"Long-term sequelae are common at NeuroZika."

"The state of the ZIKV PCR during reverse transcription at admission can inform the prognosis and should therefore be taken into account in the management of hospitalized patients."

Zika virus news

Zika is a viral infection that spreads primarily through the bite of infected Aedes mosquitoes and less frequently through badual transmission.

Avoiding mosquito bites Aedes is the best way to prevent a Zika infection.

Since the first human case of Zika virus in 1952, outbreaks have been reported in Africa, South-East Asia and the Pacific Islands. Zika was discovered in Brazil in May 2015, representing the first introduction of the virus into the Americas. Since then, it has spread rapidly in the Americas.

Although most people with Zika virus do not develop visible or severe symptoms, there is a risk of serious complications for the pregnant woman and her unborn child, including miscarriage and birth defects.

As of May 2015, Brazilian health officials reported an increase in Zika infections as well as a slight rise in babies born with microcephaly. Since the epidemic that began in Brazil, the CDC has confirmed that Zika virus infection during pregnancy can cause microcephaly and other serious birth defects.

Babies with microcephaly have a much smaller head than normal microcephaly and cause a range of problems including developmental disorders, seizures, hearing loss and vision loss.

Scientists are still studying other impacts of Zika infection during pregnancy. If you are pregnant or planning to become pregnant, the CDC webpage contains up-to-date recommendations on how to protect yourself.

In January 2016, the CDC issued a travel alert for areas of the world where the Zika virus is circulating. The alert recommends that pregnant women avoid visiting certain areas with Zika and women who are planning a pregnancy to consult their health care provider before traveling to these areas.

As information about Zika changes rapidly, check out the Disease Control and Prevention Centers (CDC) web page for updates and more information on the status of Zika virus in the world. United States.

Unfortunately, there is currently no vaccine or treatment for Zika virus.

The current observational study was limited to the 2016 outbreak in the French West Indies and included a sample taken from a hospital and strict selection criteria leading to a small number of patients in the cohort.

[ad_2]
Source link