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Tereza Kasaeva
WHO has fully released the new treatment guidelines for multidrug-resistant tuberculosis, or multidrug-resistant TB, and announced a package of measures to help countries fill gaps in care.
The measures were taken before World Tuberculosis Day, celebrated every year on March 24.
"To win the fight against tuberculosis, multi-sectoral responsibility, commitment and action are essential" Tereza Kasaeva, MD, PhD, Director of the WHO Global Tuberculosis Program Infectious Diseases News.
WHO presented an overview of the new guidelines for multidrug-resistant tuberculosis last year. They recommend switching to an entirely oral diet.
According to a press release, a "broader package of actions" aimed at increasing progress towards ending tuberculosis has been designed to help countries fill gaps in care, "by ensuring no one is left behind ".
WHO has described the package as including:
- an accountability framework to coordinate actions across sectors and to monitor and review progress;
- a dashboard to help countries learn more about their own epidemics through real-time monitoring – moving to electronic TB surveillance systems;
- a guide to establishing effective priorities for planning and implementing effective TB interventions based on badyzes of patient pathways to accessing care;
- ·new WHO guidelines on infection control and preventive treatment of latent tuberculosis infection;
- and a civil society working group to ensure effective and meaningful engagement of civil society.
"The framework advocates the following key principles to accelerate the progress of TB control: 1) all high-level commitments should be urgently translated into national goals with a comprehensive plan of action; (2) regular monitoring and reporting of all sectors should be activated and badured; 3) A full review of all the actions of different stakeholders should be provided, "Kasaeva explained.
In addition, electronic tuberculosis surveillance systems will help countries monitor TB cases in real time, allowing public health officials and other experts to learn more about TB. epidemics of tuberculosis occurring in their country.
"Infectious disease clinicians are a key provider of essential care for people with TB," said Kasaeva. "Clinician accountability for identification means providing high quality care to all patients by ensuring early diagnosis and treatment in accordance with WHO guidelines, drug safety surveillance, mandatory notification and report. "
Infectious Diseases News compiled a list of recent stories about TB on World Tuberculosis Day. – by Marley Ghizzone
Tuberculosis cases in the United States are at their lowest; insufficient refusal to achieve the objectives
Preliminary surveillance data indicates that the number of TB cases in the United States in 2018 has fallen to the lowest level ever reported, but the rate of progress toward elimination of the disease in the United States has slowed. Read more.
MDR-TB: A "global public health crisis"
In a recent cover, Infectious Diseases News He spoke with experts from the global effort to eliminate multidrug-resistant tuberculosis and end the tuberculosis epidemic. Read more.
Compulsory testing has helped halt the tuberculosis epidemic among homeless people in Atlanta
A comprehensive public health approach, including mandatory testing, put an end to an epidemic of drug-resistant TB in homeless shelters in Atlanta. Read more.
Tshepiso study: the preventive treatment of tuberculosis is not badociated with poor pregnancy results
The initiation of isoniazid preventive TB treatment during pregnancy is not badociated with a higher rate of poor maternal or child outcomes, according to the results of an observational study presented to CROI . A previous randomized trial had shown that its use during pregnancy entailed a higher risk of adverse effects for the mother. Read more.
FDA accepts NDA for TB treatment in combination with antituberculous regimen
TB Alliance has announced that the FDA has accepted a new application for its new anti-tuberculosis drug, pretanide, as part of a regimen used to treat extensively drug-resistant tuberculosis; Multidrug-resistant, treatment-intolerant TB; and multidrug-resistant tuberculosis not refractory to treatment. Read more.
Rebadured: Short-course tuberculosis treatment is safe for adults infected with HIV on dolutegravir
A short-course regimen aimed at preventing tuberculosis has been shown to be safe for HIV patients on dolutegravir treatment, without reducing the effectiveness of the anti-HIV drug. Read more.
Social intervention in Brazil increases tuberculosis cure rate by 7.6%
The Bolsa Familia program – a conditional cash transfer program in Brazil – directly affects tuberculosis treatment outcomes, demonstrating a cure rate of 7.6%. Read more.
Undernutrition is a powerful accelerator of the TB epidemic
Undernutrition, which affects nearly 800 million people worldwide, is a "potent accelerator" of the global TB epidemic, which is affecting the incidence of disease and treatment outcomes in the world. infected patients. Read more.
One study demonstrates the cardiac safety of Bedaquiline plus Delamanid for MDR-TB
Data from the Phase 2 study presented at CROI demonstrated the cardiac safety of the combined use of bedaquiline and delamanide – two new anti-tuberculosis drugs – in patients with multidrug-resistant tuberculosis receiving treatment multidrogue background. Read more.
Experts suggest screening for tuberculosis in the urine for all HIV-infected patients
In resource-limited settings, screening for urine-based tuberculosis of all hospitalized HIV-admitted patients is a cost-effective strategy that could increase their life expectancy. Read more.
Reference:
WHO. WHO consolidated guidelines on the treatment of drug-resistant tuberculosis. https://www.who.int/tb/publications/2019/consolidated-guidelines-drug-resistant-TB-treatment/en/. Accessed March 21, 2019.
Disclosure: Kaseva is employed by WHO.
Tereza Kasaeva
WHO has fully released the new treatment guidelines for multidrug-resistant tuberculosis, or multidrug-resistant TB, and announced a package of measures to help countries fill gaps in care.
The measures were taken before World Tuberculosis Day, celebrated every year on March 24.
"To win the fight against tuberculosis, multi-sectoral responsibility, commitment and action are essential" Tereza Kasaeva, MD, PhD, Director of the WHO Global Tuberculosis Program Infectious Diseases News.
WHO presented an overview of the new guidelines for multidrug-resistant tuberculosis last year. They recommend switching to an entirely oral diet.
According to a press release, a "broader package of actions" aimed at increasing progress towards ending tuberculosis has been designed to help countries fill gaps in care, "by ensuring no one is left behind ".
WHO has described the package as including:
- an accountability framework to coordinate actions across sectors and to monitor and review progress;
- a dashboard to help countries learn more about their own epidemics through real-time monitoring – moving to electronic TB surveillance systems;
- a guide to establishing effective priorities for planning and implementing effective TB interventions based on badyzes of patient pathways to accessing care;
- ·new WHO guidelines on infection control and preventive treatment of latent tuberculosis infection;
- and a civil society working group to ensure effective and meaningful engagement of civil society.
"The framework advocates the following key principles to accelerate the progress of TB control: 1) all high-level commitments should be urgently translated into national goals with a comprehensive plan of action; (2) regular monitoring and reporting of all sectors should be activated and badured; 3) A full review of all the actions of different stakeholders should be provided, "Kasaeva explained.
In addition, electronic tuberculosis surveillance systems will help countries monitor TB cases in real time, allowing public health officials and other experts to learn more about TB. epidemics of tuberculosis occurring in their country.
"Infectious disease clinicians are a key provider of essential care for people with TB," said Kasaeva. "Clinician accountability for identification means providing high quality care to all patients by ensuring early diagnosis and treatment in accordance with WHO guidelines, drug safety surveillance, mandatory notification and report. "
Infectious Diseases News compiled a list of recent stories about TB on World Tuberculosis Day. – by Marley Ghizzone
Tuberculosis cases in the United States are at their lowest; insufficient refusal to achieve the objectives
Preliminary surveillance data indicates that the number of TB cases in the United States in 2018 has fallen to the lowest level ever reported, but the rate of progress toward elimination of the disease in the United States has slowed. Read more.
PAGE BREAK
MDR-TB: A "global public health crisis"
In a recent cover, Infectious Diseases News He spoke with experts from the global effort to eliminate multidrug-resistant tuberculosis and end the tuberculosis epidemic. Read more.
Compulsory testing has helped halt the tuberculosis epidemic among homeless people in Atlanta
A comprehensive public health approach, including mandatory testing, put an end to an epidemic of drug-resistant TB in homeless shelters in Atlanta. Read more.
Tshepiso study: the preventive treatment of tuberculosis is not badociated with poor pregnancy results
The initiation of isoniazid preventive TB treatment during pregnancy is not badociated with a higher rate of poor maternal or child outcomes, according to the results of an observational study presented to CROI . A previous randomized trial had shown that its use during pregnancy entailed a higher risk of adverse effects for the mother. Read more.
FDA accepts NDA for TB treatment in combination with antituberculous regimen
TB Alliance has announced that the FDA has accepted a new application for its new anti-tuberculosis drug, pretanide, as part of a regimen used to treat extensively drug-resistant tuberculosis; Multidrug-resistant, treatment-intolerant TB; and multidrug-resistant tuberculosis not refractory to treatment. Read more.
Rebadured: Short-course tuberculosis treatment is safe for adults infected with HIV on dolutegravir
A short-course regimen for the prevention of tuberculosis has been shown to be safe for HIV patients on dolutegravir treatment, without reducing the effectiveness of the anti-HIV drug. Read more.
Social intervention in Brazil increases tuberculosis cure rate by 7.6%
The Bolsa Familia program – a conditional cash transfer program in Brazil – directly affects tuberculosis treatment outcomes, demonstrating a cure rate of 7.6%. Read more.
Undernutrition is a powerful accelerator of the TB epidemic
Undernutrition, which affects nearly 800 million people worldwide, is a "potent accelerator" of the global TB epidemic, which is affecting the incidence of disease and treatment outcomes in the world. infected patients. Read more.
One study demonstrates the cardiac safety of Bedaquiline plus Delamanid for MDR-TB
Data from the Phase 2 study presented at CROI demonstrated the cardiac safety of the combined use of bedaquiline and delamanide – two new anti-tuberculosis drugs – in patients with multidrug-resistant tuberculosis receiving treatment multidrogue background. Read more.
Experts suggest screening for tuberculosis in the urine for all HIV-infected patients
In resource-limited settings, screening for tuberculosis in the urine of all hospitalized HIV-infected patients is a cost-effective strategy that could increase their life expectancy. Read more.
Reference:
WHO. WHO consolidated guidelines on the treatment of drug-resistant tuberculosis. https://www.who.int/tb/publications/2019/consolidated-guidelines-drug-resistant-TB-treatment/en/. Accessed March 21, 2019.
Disclosure: Kaseva is employed by WHO.
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