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New research has revealed that laboratory female mice lose less weight and maintain control of their blood glucose levels when they are fed a diet high in fats and carbohydrates compared to male lab mice. The results suggest that the popular ketogenic diet may not be suitable for everyone. ( pixabay )
Many swear that the ketogenic diet contributes to weight loss, but men could reap more benefits than women from the meal plan high in fats and carbohydrates.
A new study presented at the annual meeting of the Endocrine Society revealed that, in animal models, female mice had not demonstrated the metabolic benefits of keto, including weight loss and weight loss. improved glycemic control.
"Our results in mice suggest that women on the ketogenic diet are less likely than men to experience significant fat loss and are more likely to have poor blood glucose control," said Jesse Cochran, lead investigator of the ketogenic diet. # 39; study and research badistant at the University of Iowa. "These findings may help explain the differences in the rate of success of this diet between the bades."
Ketogenic diet on mice
For the study, the researchers fed male and female laboratory mice with a normal or ketogenic diet. The normal or control group received 47% carbohydrate, 19% protein and 7% lipid. Meanwhile, the keto group received 75% lipids, 8% protein and 3% carbohydrates.
After 15 weeks, the female mice in the keto group showed insufficient control of their blood glucose. They also have not lost significant weight. In male mice, however, weight loss and sustained blood sugar control were reported in the ketogenic diet group.
The researchers noted that the male mice of the ketogenic diet also had an aggravated nonalcoholic fatty liver disease.
Cochran has hypothesized that estrogen might explain why female mice do not reap the promised benefits of the ketogenic diet. To test, she removed the ovaries from some female mice and then fed them with a normal or ketogenic diet. She discovered that female mice whose ovaries had been removed had weight loss after eating high fat and high carbohydrate meals.
Results may vary
The researchers suggested that menopausal women would have more to gain from a ketogenic diet.
Cochran also stated that the study only proved that not everyone would achieve the same results with keto or any other diet derived from this material. The researchers said people should consult their doctor or dietician before dieting to lose weight or for health reasons.
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