Girls with early puberty may develop a migraine



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Washington D.C .: Adolescent girls who reach early puberty may also be more likely to develop migraines, suggest researchers.

"We know that the percentage of girls and boys who suffer from migraine is about the same until the rules begin. When the menstrual period begins in girls, the prevalence increases dramatically, but our data suggest that this happens even before that, "said Vincent Martin, one of the researchers in the study.

About 10% of school-aged children suffer from migraine, according to the study presented to the American Headache Society. As the teenage age approaches, the incidence of migraine rises rapidly among girls and by age 17, about 8% of boys and 23% of girls had already migrated.

The girls were between 8 and 20 years old and the study took place over a period of 10 years starting in 2004. The girls enrolled in the study between 8 and 10 years were examined during of the study visit every six to 12 months.
The researchers determined when they showed the first signs of thelarche (breast development), pubarche (pubic hair growth) and menarche (early menses).

The girls answered a questionnaire on headaches to find out if they were suffering from migraine, the absence of migraine or probable migraine; the latter is defined as meeting all the diagnostic criteria for migraine, except one. The average age at which they responded to the survey was 16 years old.
Of those surveyed, a headache was diagnosed in 85 girls (11%), while 53 (7%) had a migraine and 623 (82%) had no migraine.

The researchers found that girls with migraine had an earlier age of the lip (breast development) and onset of the first rules (rules) than those without having migraine.
On average, breast development occurred four months earlier in migraine patients while menstruation began five months earlier. There was no age difference of pubarches (development of pubic hair) between migraine sufferers and non-migraine sufferers.

"There was a 25% increase in the risk of migraine than every year earlier when a girl was experiencing a seizure or menstruation. This suggests a strong relationship between precocious puberty and adolescent migraine development, "said Susan Pinney, the study's lead researcher.

The age of onset of the disease, pubarche or menarche does not differ between those who have a probable migraine and those who do not migrate, Pinney said.
Previous research has suggested that migraine often begins with the onset of menstrual cycles during menarche among teenage girls. But this study looks at the early stages of puberty, such as larvae and pubarche, Martin explained.

"It is quite novel to suggest that migraines can occur before the onset of menstruation. At each of these stages, different hormones begin to appear in girls. During pubarche, testosterone and androgens are present, and during the seizure, the very first exposure to estrogen. Menarche occurs when a more mature hormonal pattern appears. Our study implies that the very first exposure to estrogen could be the starting point of migraine in some teenage girls. This is perhaps the Big Bang theory of migraine, "Martin said.

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