High Cardiovascular Risk Characteristics in China | Annals of Internal Medicine



National Center for Cardiovascular Diseases, Beijing, People's Republic of China (J.L., H.Y., W.B., Y.L.)

Yale University, New Haven, Connecticut, Y.L.

Yale School of Medicine, New Haven, Connecticut (W.S., H.M.K.)

Medical Campus of the University of Colorado at Anschutz, Aurora, Colorado (F.A.M.)

Recognition: The authors thank Professor Lixin Jiang, responsible for designing the design and implementation of the Chinese project PEACE Million Persons, designed this article with Dr. Lu and contributed to critical reviews of the first version of the manuscript. The authors also thank all participants in the study. They appreciate the contributions of the National Center for Cardiovascular Disease and the Yale – New Haven Hospital Results Research and Evaluation Center project teams in the field of design and operations. projects, including data collection by Yang Yang, Jingwei Yang, Jianlan Cui, Wei Xu, Bo Gu, Li Xi, Chaoqun Wu, Hao Dai, Hui Zhong and Minghui Zhang. The authors thank the Ministry of Finance of China and the National Health Commission of China for their financial assistance. They also thank all provincial and regional officers and research staff in the 31 provinces for collecting data and taking samples.

Grant: With grants 2017-I2M-2-002, 2017-I2M-B & R-02, 2016-12M-1-006 and 2016-12M-2-004 from the Ministry of Finance of China and the National Commission of the health of China; the CAMS Innovation Fund for Medical Science; 2017YFC1310801 and 2017YFC1310803 grants the national key research and development program of the Chinese Ministry of Science and Technology; B16005 Project 111 grant from the Ministry of Education of China; and grant 2017330003 from PUMC Youth Fund and Fund for Basic Research for Central Universities.

Disclosures: Dr. Schulz reports the personal expenses of Hugo Health outside of the submitted work. Dr. Masoudi reports travel expenses paid by the China Oxford Center and holds the position of Chief Medical Officer for the National Cardiovascular Data Registry of the American College of Cardiology, apart from the submitted work. Dr. Krumholz reports personal fees from UnitedHealth Group, IBM Watson Health, Element Science and Aetna; reports grants from Medtronic, the US Food and Drug Administration and Johnson and Johnson; is the founder of Hugo Health; and has contracted with the Centers for Medicare & Medicaid Services to develop and maintain hospital performance measures outside of the submitted work. The unnamed authors here have revealed no conflict of interest. Disclosures can also be found at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M18-1932.

Disclosures of the editors: Christine Laine, MD, MPH, editor-in-chief, says his wife holds stock / asset purchase options with targeted diagnoses and therapies. Darren B. Taichman, MD, PhD, editor, says that he has no financial relationship and no interest in disclosing. Cynthia D. Mulrow, MD, MSc, Associate Editor, says she has no relationship or interest in disclosing. Deborah Cotton, MD, MPH, Associate Editor, says she has no financial ties and no interest in disclosing. Jaya K. Rao, MD, MHS, Associate Editor, says she has stock / stock options at Eli Lilly and Pfizer. Sankey V. Williams, MD, deputy editor, says that he has no financial relationship and no interest in disclosing. Catharine B. Stack, PhD, MS, Associate Editor of Statistics, says she owns shares in Proctor & Gamble, Pfizer and Johnson & Johnson.

Repeatable Research Statement:Study protocol: Available at http://dx.doi.org/10.1136/bmjopen-2015-010200. Statistical code: Available from Dr. J. Lu (e-mail, [email protected]). Dataset: Unavailable.

Corresponding author: Jiapeng Lu, MD, Ph.D., National Center for Clinical Research on Cardiovascular Diseases, State Laboratory of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Medical College of China Beijing Union, Road 167 Beilishi, Xicheng District Beijing 100037, People's Republic of China; email, [email protected]

Address of the current author: Drs. J. Lu and Bilige, Mr. Yang and Mr. Li: National Center for Clinical Research on Cardiovascular Diseases, State Laboratory for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Beijing Medical College, No167 Beilishi Road, Xicheng District, Beijing, 100037, People's Republic of China.

Drs. Y. Lu, Schulz and Krumholz: Center for Results Research and Evaluation, Yale University / New Haven Hospital, 1 Church Street, Suite 200, New Haven, Connecticut 06510.

Dr. Masoudi: Division of Cardiology, Anschutz Medical Campus of the University of Colorado, 12401 East 17th Avenue, Aurora, Colorado 80045.

Author contributions: Design and design: J. Lu, H.M. Krumholz.

Analysis and interpretation of the data: J. Lu, Y. Lu, F. A. Masoudi, H. M. Krumholz.

Article Writing: J. Lu, Y. Lu, W. Schulz, F. A. Masoudi.

Critical revision of important intellectual contents: Y. Lu, W. Bilige, Y. Li, W. Schulz, F. A. Masoudi, H. M. Krumholz.

Final approval of the article: J. Lu, Y. Lu, Yang H., Bilige W., Li Y., Schulz W., Masoudi F., H.M. Krumholz.

Collecting and Assembling Data: J. Lu, H. Yang, W. Bilige.


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