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A study suggests that if you suffer from high blood pressure, the consumption of fish, seafood and a predominantly vegetarian diet can help reduce the symptoms of heart disease badociated with hypertension .
Consumption of fish, seafood and compound called trimethylamine N-oxide (TMAO), known to improve heart health, said researchers from the Warsaw Medical University in Poland. The study showed that a low-dose treatment of TMAO reduced cardiac thickening (cardiac fibrosis) and markers of heart failure in an animal model of hypertension. "Our study provides new evidence of a potential beneficial effect of a moderate increase in plasma TMAO on the overloaded heart of pressure," the researchers said.
For the study published in the American Journal of Physiology – Cardiac and Circulatory Physiology, the researchers badyzed the effect of TMAO on rats, which have a genetic tendency to develop high blood pressure. One group of hypertensive rats received low dose TMAO supplements in their drinking water, and another group received pure water. They received TMAO treatment for 12 or 56 weeks and were evaluated for heart and kidney damage as well as for high blood pressure.
It seems that a diet rich in fish and vegetarian is badociated with a significantly higher plasma TMAO. (Trimethylamine N-oxide) as diets rich in red meat and eggs, considered to increase cardiovascular risk. (Shutterstock)
The results showed that TMAO treatment did not affect the development of arterial hypertension in any spontaneously hypertensive rats. However, the condition of animals receiving the compound was better than expected, even after more than a year of low-dose TMAO treatment. In addition, an increase of four to five times in the plasma TMAO does not exert any negative effect on the circulatory system. This contrasts with previous research that showed that plasma blood levels of TMAO – and the risk of heart disease – increased after eating red meat and eggs, the researchers said.
"It seems that a diet rich in fish and vegetarian, is badociated with a significantly higher plasma TMAO than diets rich in red meat and eggs, considered to increase cardiovascular risk," said the researchers. .
"However, further studies are needed to evaluate the effect of TMAO and TMA on the circulatory system."
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First Publication: 08 Nov 2018 12:37 IST
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