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Poliomyelitis is on the verge of complete eradication, with only 22 cases reported worldwide in 2017.
A new polio vaccine that does not require refrigeration may one day be used in the Worldwide Researchers Bring One Last Stroke to Infectious Disease That Affects Children Under Five
Injectable vaccine developed by researchers at the University of Southern California (USC) is freeze-dried in Canada powder and can be stored at
When tested on mice, the new vaccine offered complete protection against the polio virus, the researchers said.
"Stabilization is not a stealth science, which most academics do not think about." pay close attention to this area, "said lead author, Woo-Jin Shin, of the USC Keck School of Medicine.
" However, as wonderful are the drugs or the vaccines , if they are not stable enough transported, it does not do much good, "Mr. Shin added.
The study appears in the journal mBio.
By eliminating the # By freeze-drying, researchers have created stable temperature vaccines for measles, typhoid, and meningococcal disease, but scientists have not been able to make a polio vaccine that retains its effectiveness through lyophilization and freeze-drying. to rehydration
Dr. Shin and his colleagues used two laboratory techniques – liquid chromatography and high throughput screening – to badyze a high volume of ingredients and preparations up to the same time. to find them One that works
They now hope that a foundation or company will take over the project to fund human studies and the commercialization of the injectable vaccine.
Poliomyelitis is on the market. Complete eradication is about to be eradicated, with only 22 cases reported worldwide in 2017. The highly infectious disease, which causes lifelong paralysis and disability, mainly in young children, is a memory that erases in many places. Yet in countries with uneven immunization rates, young children are at risk.
The main obstacle to complete eradication is the creation of a stable temperature vaccine to be used in developing countries where refrigeration may not be available. Polio cases have recently been reported in Nigeria, Papua New Guinea, Syria and Pakistan.
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