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Toronto: While there is a growing need to reduce the use of antipsychotics, trazadone – a drug frequently used as an alternative – is badociated with a similar risk of falls and major fractures in people older patients than atypical antipsychotics, warns a new study. Although the evidence for efficacy is limited, antipsychotics and trazadone, an antidepressant also used for sleep problems, are commonly prescribed to patients with dementia.
The study revealed that patients treated with trazadone had a rate of major falls and fractures, including hip fractures. fractures similar to those of atypical antipsychotics. In addition, trazadone has been badociated with a lower risk of death in patients taking the drug. "While clinicians seek to reduce the use of antipsychotics, we should not consider trazadone as a uniformly safer alternative to atypical antipsychotics, as the use of trazodone was badociated with a comparable risk of falls." and significant osteoporotic fractures to atypical antipsychotics, "said Jennifer Watt. St. Michael's Hospital in Toronto
For the study, the team included 6,588 elderly people newly dispensed with Trazadone and 2,875 newly administered atypical antipsychotic drugs. According to the study, the rate of dementia is nearly 25% in people over 85 years old. (IANS)
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