Trazadone causes falls and fractures in the elderly: a study

While it is increasingly necessary to reduce the use of antipsychotics, trazadone – a drug frequently used as an alternative – is badociated with a similar risk of falls and major fractures in people older patients than atypical antipsychotics, warns a new study.

the effectiveness is limited, antipsychotics and trazadone, an antidepressant also used for sleep disorders, are commonly prescribed to patients with dementia.

The study found that trazadone patients had a significant fall and fracture rate, including similar hip fractures. to patients receiving atypical antipsychotics.

In addition, trazadone was badociated with a lower risk of death in patients taking the drug.

"While clinicians opt for a reduction in the use of antipsychotics, we should not consider trazadone as a safer alternative." Atypical antipsychotics, as the use of trazadone was badociated with a comparable risk from major osteoporotic fractures and falls to atypical antipsychotics. "- Jennifer Watt, researcher at St. Michael's Hospital in Toronto

For the study published in the Canadian Medical Association Journal, the team included 6,588 new people receiving trazadone and 2,875 new atypical antipsychotics.

According to the study,

"We hope that this information can be used to inform patients and caregivers of their conversations with clinicians about the benefits and risks of different treatment options. , "Said Watt.

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