Alzheimer's, the hopes of the first tests on a drug



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HOPE of an experimental drug undergoing clinical trials against Alzheimer's disease: the drug of Biogen and Eisai is called BAN2401 and – taken at the highest dose of the five doses tested during 18 months – reduced the deficit of 30% of the memory related to the disease compared to the measurable deficit in the placebo group who did not take the drug. The news was released at the Alzheimer's Association's international conference that is underway in Chicago

BAN2401, which is part of these potential Alzheimer's disease drugs that attack the depots amyloid beta (drugs that have not yet yielded the desired results), was tested in a Phase II trial at different doses and only at the highest dose (tested only in 161 patients). showed tangible results on the slowing down of cognitive decline, which may require a new phase 3 trial to switch to the licensing request to the competent bodies (Food and Drug Administration).

BAN2401 has been shown to effectively remove beta-amyloid plaques in patients' brains, which in 81% of cases went from "amyloid-positive" to "amyloid-negative" (lack of plaques in the substance) . And most importantly, BAN2401 has slowed down cognitive decline, says Jim Hendrix of the Alzheimer's Association, arguing that a new trial would be needed to define the optimal dose of the drug and see if the results achieved so far can be reproduced.

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