Antibiotic resistance in 2050 will be the leading cause of death



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In 2050, the phenomenon of antibiotic resistance will be the leading cause of death. Says with a serious warning Mauro Stronati, director of the Department of Women's and Children's Health of the IRCCS Foundation Policlinico San Matteo di Pavia. Antibiotics are a fundamental guarantee for our health, the problem arises because too many are prescribed and overused at all levels. Unfortunately, they create multidrug-resistant microorganisms when they are used inappropriately or in excess, and this will be a problem we would likely face in the next 10 years.

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Because bacteria become resistant to antibiotics
How resistance occurs
Projection

Every year in the United States, 2 million people suffer from multidrug-resistant microorganisms and 23,000 deaths, at a cost of $ 20 billion. One study calculated that as of 2050, there would be 10 million deaths each year due to multidrug-resistant microorganisms. It has been calculated that the number of cancer deaths would be 8 million. Cos, concludes Stronati, believes that the continuation of this trend in 2050 will be the leading cause of death.

WHO data

From E. coli to Staphylococcus aureus, a boom in people with antibiotic-resistant infections: there are at least half a million worldwide. The new data comes from the World Health Organization's (WHO) first report on surveillance for antibiotic resistance, but the estimate is far inferior to the actual data. In fact, to date, only data for 22 countries are available. In addition, the number does not include cases of tuberculosis resistance.

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The five most antibiotic-resistant germs
Klebsiella
The surveillance system

To date, WHO's Global Antimicrobial Surveillance System has registered 52 countries (25 high-income, 20 middle-income and 7 low-income). For the first report, 40 countries provided information on their national surveillance systems and 22 countries also provided data on levels of antibiotic resistance. The report is an essential first step in improving our understanding of the extent of antimicrobial resistance. Surveillance at the beginning, but fundamental to develop it if we want to anticipate and deal with one of the biggest threats to global public health, said Carmem Pessoa-Silva, who coordinates the WHO's new surveillance system.

The situation in Italy

In Italy, especially the bacterial species Klebsiella pneumoniae, which is resistant to almost all available antibiotics, including carbapenems. The percentage of resistance to this clbad of antibiotics in K. pneumoniae is equal to 34%, one of the highest resistance rates in Europe, with that of Greece and Romania. Italy is the European country with the highest percentage of resistance to almost all antibiotics. We use too much antibiotics and we often use them badly. The result is that resistance to these drugs increases. According to the data ofEuropean Center for Disease Prevention and ControlIn terms of consumption, Italy ranks fifth in Europe and among the countries with the highest rate of resistant micro-organisms. Especially since there are no new drugs on the horizon, the last clbad of antibiotics discovered dates back to the 1980s.

November 3, 2018 (amended November 3, 2018 | 11:37)

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