Antibiotics and vaccines: our number 1 defense



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In the era of "Dr. Google "and craft medicine, when the false news the clarity of health is an increasingly difficult task. Also difficult because doctors talk and compare often, but not with patients. With this consideration, part of Udine a first step towards change. On the occasion of the World Week on the Conscious Use of Antibiotics (from November 12 to 18), promoted byWHO – World Health Organization – The Friulian capital will be at the center of the debate, thanks to an event that explains itself: "Antibiotics and vaccines, our number 1 defense".

The national meeting is organized by the SITA (Italian Society of Infectious Treatment) and by the infectious diseases clinic of the integrated university hospital of Udine – in collaboration with the municipality Udine & # 39; Città Sane ", under the patronage of" UniUd, the College of Physicians and Dentists, and that of the pharmacists of the province – and will be held on November 17 from 10am to 12:30 pm, the Parliament of the castle. To open the event, there will be the Mayor of Udine, Pierre Fontanini.

At the speakers' table, with Matthew Bbadetti, director of the infectious diseases clinic ASUIUD, there will be the municipal councilor of health, Jeans Barillari, the teacher Pierluigi boulevard, Director of the Clinic of Infectious Diseases at the University of Bologna, and many other colleagues to talk to and answer questions from the audience. "The title says it already long – explained Bbadetti – because antibiotics and vaccines have changed the last 100 years of the history of medicine and if we can live that long, it's also thanks to The conference wants to shed light on these issues but we will do things differently, addressing the population, who will use these drugs and we will try to dispel the doubts, also highlighting the benefits of these two principles, explaining how and why when to take the antibiotics for children and the optional ones, like the flu.

That of vaccines remains a game to play. Coverage data are not always positive from influenza. Last season (2017/2018), the number of members of the FVG increased slightly, reaching about 55% among those over 65, against a national average of 53%. A total of 174 000 527 people were vaccinated after the age of 64 (about 169 000 the previous year); 39,925 people under 64 years of age with at-risk diseases. The situation changes when you enter hospitals where, among health workers, the coverage is mediocre of 11%. A slight improvement is noted in Udine, where it reaches about 14% (28% of doctors, 11% of nurses, 14.5 technicians, 9% of cases and 4% of obstetricians).

The badysis of the regional coverage (at 31 December 2017) of other vaccines, those to be done within 24 months (thus considered as born in 2015), changes: 86.6% are vaccinated against measles, 90, 6 % against whooping cough, the coverage for chickenpox drops to 79.6%, while mumps and rubella are respectively 86.5 and 86.6%, against polio, it is called 90, 5% (up after a clear decline from 2001); for meningococcus B, we go from 69% of the first dose to 28.6% of the third dose.

The minimum threshold recommended by the World Health Organization provides for a 95% coverage level for all childhood vaccinations. A still distant destination, although the numbers speak, at least in some cases like polio and measles, of a reversal of trend. The number of vaccinated has increased in recent years. And Bbadetti stressed that "we must work for universal coverage, if we can defend ourselves, why not do it?".

The situation of antibiotics is not better, but for the opposite reason. In fact, over the years, the phenomenon of antibiotic resistance has spread. Indeed, the indiscriminate use of antibiotics reduces the effect, which must however be absolutely preserved. It is precisely in this context that is the "World Week of Conscious Use of Antibiotics". In Italy too, it is a black jersey (among the first in Europe in terms of consumption, even more than double that of the countries of the North). There are too many antibiotics used by the population, who often take them without any real need and without knowing what they are used for, so much so that "we are the first in Europe to fight against the proliferation of resistant germs". More importantly, the number of people taking them without a prescription (old boxes, online shopping or other) shows no sign of decreasing. In this already complex scenario, many people are unaware of the phenomenon of antibiotic resistance. The gap between the north of the country and the south is also important, where the phenomenon is more pronounced. In Fvg, about 15 DDD (defined daily dose, Definita Giornaliera dose) per 1,000 inhabitants are consumed outside the hospital (at the territorial level), compared to a national average of about 27.

In this context, Udine has a record. Clinical trials (phase III) on new antibiotics (cefiderocol, imipenem-relebactam, rezafungin) are being created to fight against multidrug-resistant bacteria: "Still about antibiotics, the director of the Friuli Infectious Diseases Clinic launches a proposal : "Years ago, while I was still living in Genoa, we had a small booklet containing 50 questions and answers about antibiotics. Why not create version 2.0, also answering questions about vaccines? ".

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