Created in the laboratory the first mini human brain in a test tube



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It was reproduced in the laboratory the first mini human brain, literally complete and it would be a miniature organ also called organoid that contains in all cell types belonging to its most evolved part C & # 39; is the cortex . The recipe has at its disposal a laboratory to be able to study the behavior of the most complex organs or to understand the brain and to understand the origin of many neurological diseases and to be able to experiment with drugs. An interesting result was obtained in the laboratory and was published in the methods of the journal journal and is due to the American group Western Reserve University, coordinated by Professor Paul Tesar.

It seems that the technology of organelles, was really revolutionary since its beginnings because over time it allowed to reproduce human organs in test tubes from stem cells and from those who revolutionized the ability to generate and study human tissue in the laboratory. In the brain, the organs obtained were not complete until now, mainly because it does not appear to contain all the cells of the cortex and especially the oligodendrocytes that are fundamental for a healthy brain.

This is because produce myelin which does not know is a substance that envelops the connections of nerve cells and without which these cells can not communicate effectively and may also deteriorate so much that many neurological diseases derive precisely from defects in this patch, or myelin, for example or multiple sclerosis.

The researchers now seem to have managed to get the complete mini brain and have the shape of a sphere and this only thanks to the possibility of having identified a good recipe to get all bark cell types derived from induced pluripotent stem cells or reprogrammed baby dams, different types of proteins were used to induce stem cells to transform into the main cell types found at Inside the human cerebral cortex are the neurons that, as we know, are the main cells of the nervous tissue and also the astrocytes that make up the brain's supporting structure called glia.

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