Female fertility: new anti-aging techniques to rejuvenate the ovaries

After 35 years, we know that female fertility decreases rapidly and after 40, the techniques of badisted procreation are less successful. The fault of the ovarian reserve which becomes more and more rare. But the aging of the ovaries is a phrase without appeal or the process can at least partly reverse? From ovarian rejuvenation last frontier of the challenge against time in terms of maternity, we spoke on the occasion of the 34th Congress of the European Society of Human Reproduction and Embryology (ESHRE) [19659003] in which Nuria Pellicer, doctor of the hospital La Fe in Valencia, presented the results of a study conducted in collaboration with IVI (medical facility manufactured in Spain specialized in reproduction), which will soon be published on Fertility & Infertility : thanks to the stem cell transplantation technique of the woman's bone marrow in the ovarian artery, various pregnancies have been obtained and three children are born. And the third phase of the study is currently underway with budding women who are still young but already in menopause or early pre-menopause and who also have a second, less invasive pathway: reinjecting cells stumps in the area surrounding the ovary. The goal is still to promote the activation of dormant follicles, that otherwise would remain in the ovary without developing.

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Next to injection of growth factors called ovarian fragmentation (19459004), which involves a laparoscopic intervention during which a very a small part of the ovarian cortex is extracted, is tested for ovarian rejuvenation which is reduced to tiny pieces, then reinjected into the ovaries to "wake up" the oocytes and promote the genesis of new follicles.

A third technique (Augment) takes place directly on the collected oocytes In vitro fertilization, to which the pile is changed, thanks to an injection of mitochondria – source of information. cell energy – extracted from the bark of the ovarian banks.

Stop the hands of the biological clock and protect his fertile inheritance from inevitable aging, or remedies, such as chemotherapy, that can l & # 39; irreparably damage, there is finally another possibility, non-therapeutic but prevention: freeze their eggs in time. Eggs are taken with small intervention and cryopreserved through traditional slow freezing or most innovative vitrification. Once thawed, they will follow the path of in vitro fertilization. The percentages of success, in the case of the social freeze (or rather Age banking ), ie the choice of healthy women, depend a lot on the age of the sample: between 25 and 35 years of age

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