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A French French woman with cystic fibrosis since childhood died of lung cancer after receiving these organs during a transplant. After a rapid deterioration of his respiratory function, typical of cystic fibrosis, doctors decided in November 2015 to perform a lung transplant. The donor was a smoker.
The study published in Lung Cancer, conducted by doctors at the University Hospital of Montpellier, reveals: "According to the donor database, the transplanted lungs were taken from a 57-year-old man who smoked a pack of cigarettes a day for 30 years ". The examinations performed at the time of the donor's brain death had revealed no abnormalities, but by June 2017, the transplant patient had been diagnosed with cancer, had been admitted to the hospital on thoracic oncology from Montpellier and died two months later, with no possibility of cure. According to the study, the symptoms clearly recall those caused by smoking.
"The short delay between lung transplantation and the appearance of the first radiological abnormality suggests that carcinogenesis, the process that transforms normal cells into cancer cells, began during the donor's life," the authors of the study said. # 39; study. The cancer would have progressed at an abnormal rate because of the immunosuppressive treatments that the transplanted woman took to avoid organ rejection. "Given the relatively long latency of lung cancer, we suggest that transplants of smokers or recently arrested donors be considered with caution," said the doctors.
Opportunity or increased risk? The growing gap between the number of patients waiting for transplant and the available organs continues to be the main limit to the expansion of transplants, said Giovanni D'Agata, president of the "Window Rights". Despite a potential risk of disease transmission and this study warns about the risk of transplantation of these organs, the results of organ transplantation from "abnormal" donors were not badociated with the reduction of the survival of the organ and the patient.
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