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Klebsiella pneumoniae is not always dangerous but when it comes out of its habitat in the intestine, the bacteria can cause an endless series of problems, including necrotizing fasciitis, capable of killing a person in perfect health in a few days. As if that were not enough, there is a tension to which we must really pay attention.
Usually K. pneumoniae is defined as an intestinal bacterium that lazily floats inside the human digestive tract, which sometimes manifests itself in the mouth or on the skin, nor is it Not uncommon for known bacteria, it usually manifests as a common hospital infection in people who are already experiencing an attack on their own immune system.
In the past, a rather aggressive variety of the bacteria was detected in Taiwan in the 1980s, causing brain and liver abscess and necrotizing fasciitis. Unfortunately, the hypervirulent strain of K. pneumoniae (hvKp) is unlikely to be detected by early diagnosis. Until now, no diagnosis can guarantee that K. pneumoniae is a disguised strain of hvKp, at least until the damage is done now.
Researchers are working on a fundamental point; a test for chemical markers that can distinguish between two different types. Thomas Russo, head of the Division of Infectious Diseases at the University of Buffalo, as well as researchers from around the world, have found information buried in the DNA of hvKp that could be used to identify it reliably.
really be based on real concepts, but that's only the first step of the process. " Currently, there is no commercially available test to accurately distinguish between clbadical and hypervirulent strains ," explains Thomas Russo, who later reveals: " This search provides a leaf clear road about how the company can develop a test for use in clinical laboratories . "
For the moment, it is already serious enough that the World Health Organization considers the development of an antibiotic that will keep it under control until now MDR has maintained a relatively low profile, but its prevalence is increasing and health organizations are on alert.
If the hvKp evolved and was learning to resist the latest generation of antibiotics, at that time there would really be difficult times, that's why having a test to distinguish the hypervirulent strain would clearly a victory for patient care. But the general framework would provide this test to epidemiologists so that they can trace its spread as it crawls around the world and closely monitors the resistance of the bacteria.
On the development of the virus there has been news: " This last mechanism is at the origin of the death of five patients in the intensive care unit of a hospital from Hangzhou, China, which was reported earlier this year ", confirms Russo.There is much to learn about the hypervirulent strain, more cases have been reported in Asian countries than in others regions, but it is unclear if it is because it is rife.
Future research could provide more information in which it will be easy to reveal the typology of hvKp. was published in Journal of Clinical Microbiology
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