Unpublished role for aspirin: take low dose may slow down Alzheimer's disease

An unprecedented role for one of the most used drugs in the world. According to a new study conducted on a mouse model and published in the journal "JNeurosci", regular consumption of low-dose aspirin could represent a new way to curb Alzheimer's disease. Although the exact cause of progression of dementia is not yet known, the role of toxic beta-amyloid protein especially in the hippocampus, is now established. Activating the cellular process responsible for eliminating brain "waste" has therefore emerged as a promising strategy for slowing down the disease. Based on prevalence studies that demonstrate a link between aspirin and a reduced risk of Alzheimer's, Kalipada Pahan and colleagues at the Rush University Medical Center in Chicago have shown that this over-the-counter drug reduces the risk of Alzheimer's disease. amyloid plaque accumulation in mice by stimulating lysosomes, animal cell components that help clear cell debris.