The ketogenic diet or the keto diet is widely recognized for its benefits that could help lose extra weight without requiring a strict and extremely limited meal. Some people have also found this approach effective in improving blood glucose control.
However, the trend could change in the future, especially among women. A new study shows that women do not really benefit from a diet high in fats and carbohydrates.
The findings, presented at the recent ENDO 2019 meeting of the Endocrine Society in New Orleans, Louisiana, suggest that women are less likely to lose weight after following the keto diet. The researchers also discovered that such an approach could lead to problems controlling blood sugar, reported EurekAlert.
"These findings can help explain the differences in the rate of success of this diet between the sexes," said Jesse Cochran, senior research scientist and research assistant at the University of Iowa. in Iowa City.
The ketogenic diet was originally introduced to help treat people with epilepsy. It limits the consumption of carbohydrates and proteins, which encourages the body to go from burning carbohydrates to burning stored fat.
For the last study, the researchers analyzed the effects of the diet on male and female mice. The team first fed the animals with a ketogenic diet or a regular diet as a control.
The control diet provided 7% fat, 47% carbohydrate and 19% protein by weight, while the keto meal gave 75% fat, 3% carbohydrate and 8% protein by weight.
After 15 weeks, the keto-fed female mice showed no change in weight and had poor glycemic control. Meanwhile, male mice fed the same diet showed body weight loss and maintained glycemic control.
The researchers also attempted to eliminate the ovaries of some female mice to determine if estrogen plays a role in the body's response to the ketogenic diet. The results show that mice without ovaries and on keto diet had a lower weight and fat mass.
"This finding suggests that postmenopausal women could potentially perform better in terms of weight loss with the ketogenic diet compared to younger women," said Cochran.
Although this is an animal study, the team suggested that people consider consulting a doctor or expert to discuss the intent to follow a keto diet because the same problems the mouse could also occur in humans.