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Scientists have discovered a new medical breakthrough that is gradually reversing the effects of baldness by successfully repelling hair on the affected skin.
Medical scientists based in New York have activated a pathway in the brain called "sonic hedgehog".
This pathway is very active in the presence of babies in the uterus and forms hair follicles, while it stops in the skin of the elderly as well as in damaged skin.
The study examined the damaged skin of experimental mice, focusing on fibroblasts, which secrete collagen (the protein responsible for maintaining the shape and strength of skin and hair).
Scientists have also been interested in fibroblasts because they help guide some of the biological processes involved in healing.
The team, led by Dr. Mayumi Ito, has activated the "Sonic Hedgehog" path that cells use to communicate with each other.
By stimulating contact between these cells, hair growth was observed within 4 weeks in the mouse.
According to the experience published in Nature Communications, hair roots and skeletal structure began to appear after nine weeks.
Until now, scientists have badumed that the accumulation of scars and collagen in damaged skin was at the root of the impossibility of regrowing hair.
"We know that it is a signaling problem in very active cells during our development in the uterus, but weaker in mature skin cells with age," said Dr. Eto & # 39; o. In covered wounds. "
Dr. Eto's explained that hair regrowth on damaged skin is a necessary need not available in medicine because of the deformity badociated with trauma, burns and other injuries.
At the same time, other trials have revealed a higher risk of tumors badociated with lane stimulation. To avoid these risks, the team activated the fibroblasts located just beneath the surface of the skin, where the hair roots first appear.
This study can help develop better medications to restore hair growth.
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