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A bad night's sleep has been badociated with Alzheimer's disease, but so far very little is known about how sleep disorders lead to the spread of the disease.
A new study in humans and mice revealed that sleep deprivation increased levels of primary protein in Alzheimer's disease, "Tao", according to " Daily Mail ".
During the follow-up period in mice, researchers from the University of Washington's Faculty of Medicine in St. Louis showed that the inability to sleep accelerates the spread of toxic concentrations of Tao protein of the brain.
Lack of sleep helps to make the disease worse and a good night's sleep can help keep the brain healthy, according to the study published in the journal Science.
"What's interesting in this study is that it suggests that real factors, such as sleep, can affect the speed of spread of the disease in the brain," said Dr. David Holtzmann, senior author, head of the department of neurology.
Holtzmann added: "We have identified the badociation of sleep problems and Alzheimer's disease in part with a different protein from Alzheimer's disease, beta-amyloid, and this study shows that sleep disorders result in a rapid increase of the destructive protein and their spread over time. "
"Our brains need time to recover from the current stress and we still do not know if getting enough sleep with age will protect against Alzheimer's disease, but it's harmless," Holtzmann says. "We must have a good night's sleep, These and other data suggest that it could even help to delay and slow down the disease if its signs begin to appear."
There is usually a "tau" in the brain, even in healthy people, but under certain conditions it can be grouped in the form of a ripple that afflicts nearby tissues and threatens cognitive decline.
Scientists say that Tao protein is regularly released during waking hours through the normal work of thought and action, and then decreases the level of protein during sleep during the night. Sleep deprivation depends on this natural cycle of protein, which allows it to accumulate in harmful combinations.
In people with Alzheimer's disease, the protein tends to appear in parts of the brain important to the memory, the hippocampus and the inner nasal cortex, before spreading to others. parts of the brain.
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