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The study found that Porphyromonas gingivalis, the leading cause of gum disease, was only able to reach the mouse brain six weeks after infection. The damage in brain memory centers of these mice may explain earlier evidence that people with long-term gum disease are 70% more likely to develop dementia.
Scientists now believe that bacteria can cause Alzheimer's disease in humans after discovering the toxic enzymes produced by brain, cerebrospinal fluid and rodent games diagnosed with the disease.
The study led the American company Curexyme, which claims that Porphyromonas gingivalis bacteria play a "central role" in the development of Alzheimer's disease.
"This study is an important success in understanding how we can stimulate Alzheimer's disease and create a new treatment," said CEO Casey Lynch.
Gingivitis, which causes bad breath and bleeding gums, has been badociated with chronic health problems, including heart disease.
It was thought that oral bacteria could enter the bloodstream, entering cells believed to protect the brain and spreading over the brain for several years. Now, scientists have shown that Porphyromonas gingivalis can actually pbad from the mouth to the brain in mice.
Once infected with gingivitis, these animals showed brain lesions in the hippocampus, the critical area of brain memory.
The mice also showed an accumulation of beta-amyloid, one of the devastating proteins of the brain believed to accumulate causing dementia.
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