"T cells" of HIV. New hope for AIDS vaccine production

An international research team has managed to find new evidence that can contribute to global efforts to produce an HIV vaccine.

In a study published in the journal Nature Communications, Mark Brockman of Simon Fraser University in Britain and researchers from the University of KwaZulu-Natal in South Africa discovered a link between the control of the Infection and the response of T cells to different HIV sequences.

Brookman explains the importance of what they found in a report published by Simon Fraser University on February 1: "HIV adapts to the human immune system by modifying its sequence to avoid anti-viral T cells."

"In order to develop an effective vaccine against the virus, we must generate an immune response that the virus can not easily escape."

It is estimated that the "cell" of the human T cell comprises 20 to 100 million unique unique genes that can be distinguished by their T cell receptors (TCRs), few of which are important in the response to the virus.

"We were able to access new laboratory methods to identify anti-virus T cells and badess their ability to recognize different sequences of HIV," Brookman said.

Despite this success, Brookman says that much remains to be done to create an effective vaccine, but at the same time looks forward to having taken a significant step in achieving this goal. "Comprehensive approaches to badess the ability of T cells to recognize The various HIV sequences, such as those we have developed, provide important information to help design and test new vaccination strategies."