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The researchers report that women who do not accumulate fat in the bad risk getting diabetes and a heart attack.
Health experts have long warned that weight gain is dangerous for health, but new research reinforces the theory that the fat-accumulating part has a big impact.
The researchers discovered that it is safer to gain weight in the thigh area than to accumulate around the abdomen or store around key organs such as the liver or the pancreas. Scientists from the University of (Cambridge) in Britain believe that some women are less able to store fat in the area. Thigh: This exposes them to a risk of type 2 diabetes and heart disease because, when fat is not accumulated in the bad and thighs, this fat circulates around the abdomen and major organs such as the liver and the pancreas.
"These facts may seem illogical," said Dr. Luca Lotta, professor at the Epidemiology Unit of the Medical Research Council at the University of Cambridge. "Low fat accumulation in the bad can not increase the risk of type 2 diabetes and fecal convulsions.
"We think this is due to the inability to break down the genes to store the excess calories in the thigh area safely.This means that people with this genetic makeup prefer to store the gene." excess fat in the liver, muscle, or pancreas or in their blood • Fat is spread, which can increase the risk of disease.
"We are trying to understand if some of the genes identified in the study could be appropriate targets for drug development in the future, but this process may take several years.
Scientists have studied the genetic profiles of more than 600,000 women and identified more than 200 genotypes qualifying people with a higher waist-to-hip ratio, an "apple-shaped" body measure compared to a fat-free leg.
Scientists have identified two specific sets of genetic variants, one that reduces fat around the thighs and another at the waist and abdomen.
"We found that the two genotypes we identified were badociated with a higher risk of type 2 diabetes and heart attacks," said Dr. Claudia Langenberg.
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