Histamine enhances memory



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Humans have long sought ways to preserve their memories and are able to remember all their details. Strange as it may seem, science will probably find a way to improve the quality and longevity of our memories.

A medical study has concluded that taking drugs containing histamine helps improve our long-term memory.

This compound plays different roles in the body, especially in the immune system, according to an article in Tim Newman's "Medical News Today".

In recent years, researchers have shown an interesting relationship between high levels of histamine and improvements in memory, but their understanding of the relationship is still incomplete.

In the study conducted by researchers Yuji Ikejaya and Hiroshi Nomura and a team of scientists from the University of Tokyo in Japan, researchers studied data from 38 young men and women in the middle of the third decade and asked them to save images for everyday needs such as watches and glbades.

After a few days, the team tested the participants and made them look at original images mixed with images they had never seen and asked them to identify the images they had seen a few days ago.

The researchers repeated the experiment after seven to nine days, with some participants receiving a placebo, while others were receiving a drug that promoted histamine levels in the brain.

Improve memory but not everyone
Histamine had a positive effect on the memory test results of some participants, as expected. Histamine helped people with memory problems to remember more images than in the first set of trials.

Histamine stimulated long-term memory but did not improve other cognitive abilities.

The researchers tried to show a specific image of the participants, but they did not remember them. After taking medication containing histamine, these participants were able to remember the photo.

"For any student who wishes to use this drug as a catalyst for study, we must first warn him of his health risks and tell him that we have not yet tested his ability to help anyone learn and save new things, "said team leader Yuji Ikejaya.

However, the positive effects of drug use have not been observed in all people.

In general, participants were able to recall some images during the first experiment, but they could not remember it as easily after taking the drug, which promotes histamine levels in the brain.

Scientists believe that this sudden contradiction can involve "echoes".

Echo echo
In the case where the signal is weak (the signal leading to the recovery of memory), so that the sensor is not recognized as possible, intervening and reinforcing the incident echo. The principle of this echo is the addition of the so-called "white noise" to the original signal so that it is reflected in the sounds that make up the noise, which facilitates its identification, its separation and its detection.

Dr. Ikejaya and his colleagues believe that the brain is able to store information according to the gradient system. We have to move the nerves and gradually reach a certain level to be able to remember something. Once we have exceeded this level, we can remember better.

Scientists believe that histamine will push the brain beyond this level and encourage memorization of neurons, making it very easy for a person to access his memories.

Conversely, if the memory can exceed this normal level, the addition of histamine, which in turn adds a lot of white noise, as well as additional nervous activity, hinders the recovery of memories.

The researchers studied the effect of the drug on mice. In general, if the mouse has two games, the new and the other familiar, he will prefer the new game. However, the mice have forgotten the novelty of the first game and have given the same attention to both games . For their part, the researchers treated mice with one of two drugs that promote histamine.

After taking the drug, the mice remembered the games for 29 days instead of just three days, but the effect of the drug on the memory did not last long, as the mice returned to treat the games as unknown and pay equal attention.

When scientists explained the mouse brain, they found that histamine levels were particularly high in the cerebral cortex, which involved sharing some sensory information and some cognitive functions, not to mention their great importance for Memory.

Although this type of research is relatively new, researchers predict that histamine will have multiple uses. Understanding the properties of this organic compound can help doctors and researchers create new treatments for Alzheimer's disease and dementia.

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