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"Al Jazeera" – Ahmed Al-Qarni:
A recent scientific study conducted at the King Faisal hospital and specialized research center has revealed a link between HPV infection and some head and neck cancers in patients in Saudi Arabia.
The study was conducted in the biological radiology research laboratory of the Department of Medical Physics of the Hospital Research Center and included 285 patients, 28 patients with pharyngeal tumors, 257 patients with tumors of the oral cavity and a was treated at the King Faisal hospital and specialized research center from 2002 to 2016.
The study showed that the practice of smoking was closely related to the low overall recovery rate of the tumor after treatment, in addition to other factors, including the evolution of the tumor stage and of l & # 39; age.
The study indicated that early medical intervention in the early stages of the tumor more narrowly increases the recovery rate compared to advanced stages often requiring chemotherapy and radiation therapy.
Dr. Ghazi Al-Subeeh, the principal investigator of the study, said that although the rate of pharyngeal cancers in Saudi Arabia has decreased relative to global rates, it has increased more than twice between 2009 and 2016 compared to the period from 2002 to 2008, and accompanied a steady increase in the incidence of HPV.
Dr. Ali Al Zahrani, executive director of the Research Center of King Faisal Hospital in Riyadh, said that this study is one of the fruits of the overall focus of the Center, putting the 39 focus on support for national research focused on studying the characteristics of the disease in Saudi Arabia, which will be reflected positively in the level of specialized health care for patients. In line with the vision of the 2030 Kingdom, which provides a framework for the transition to a knowledge-based society, one of the most important scientific research.
The study focused on the badysis of HPV-infected patients and on the level of p16INK4a protein (p16) produced by a tumor suppressor gene and their badociation with the cure rate of the tumor. disease. The study concluded that the high level of p16 protein, alone or badociated with HPV infection in these patients, narrowly increased the rate of recovery.
As a result, the study recommended that the badysis of p16 protein and HPV testing be included in the treatment plan for head and neck cancer patients in Saudi Arabia after having proven their effect on healing of the disease.
This five-year study was the first of its kind in Saudi Arabia. It included a research team consisting of Dr. Ghazi Al-Subaih, Najla Al-Harbi, research technicians, Sara Ben Jdea, Department of Radiological Research, Department of Medical Physics, and Department of Laboratory Medicine. Medhat Al-Sibai of the Department of Radiation Oncology and Wajdan Al-Qahtani of the Tissue Department of King Saud University of Riyadh.
The study was published last June in the influential journal Cancer International.
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