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To expandMIT engineers have designed new combinations that deliver drugs directly to cartilage, which can penetrate the depth of the cartilage and deliver drugs that can heal damaged tissue.
"Osteoporosis" is a disease that causes severe joint pain that affects more than 20 million people in the United States alone. However, some treatments can reduce pain, but no treatment can reverse or slow the damage. Cartilage badociated with the disease.
"This method is the best way to directly access damaged cells and introduce different types of treatments that alter the patient's motor behavior," said Dr. Paola Hammond, head of the department's Chemical Engineering Department. # 39; Institute. She is also a member of the Koch Institute of Integration.
In a study on rats, several researchers showed that the administration of an experimental drug called insulin-like growth factor (IGF-1) with this new substance avoids cartilaginous damage in a way significant and more effective than the injection of the drug into the same joint.
A number of previous studies have shown that insulin-like growth factor (IGF-1) can help renew cartilage in animals, but many arthritis medications that have gave promising results in animal studies did not give good results Clinical Trials
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